“…In Quantitative Structure-Property Relationship (QSPR) and Quantitative Structure-Activity Relationship (QSAR) investigations, these topological descriptors are utilized to estimate the physicochemical and/or biological characteristics of molecules [20,41]. Several degree, spectrum, matching, and distance-based topological descriptors have been suggested and explored in the literature [37,42,5], some of the interesting indices are Sombor index, Steiner Gutman Index, Estrada index and Laplacian Estrada index of a graphs, see [43,38,39,44]. One of the oldest topological indices and most investigated is the Wiener index, after the successful of this index, Gutman et al [16] introduced the generalization of the Wiener index for a acyclic graph known as szeged(Sz) index.…”