The adsorption of polyaromatic hydrocarbons on natural and chemically modified asbestos fibers

The molecular epidemiology of asbestos and tobacco in lung cancer

“…Possibly the best mechanistic explanation for the multiplicative effects of asbestos and cigarette smoking involves a model where asbestos fibers serve as a vehicle to deliver concentrated doses of tobacco carcinogens to the nucleus of the target cell (Brown et al, 1983;Gerde and Scholander, 1988;Lakowicz et al, 1980;Menrad et al, 1986). Surfactant phospholipids coating the lung epithelium adhere to the asbestos fibers creating a lipid bilayer where hydrophobic carcinogens such as polycyclic aromatic hydrocarbons (PAH's) may solubilize Scholander, 1988, 1989).…”

An Infrared Spectroscopic Study of the Vapor Adsorption of Nitroglycerin and Pentaerythritol Tetranitrate on Chrysotile Asbestos

“…Chrysotile's adsorption of benzo [a]pyrene, a component of cigarette smoke with mutagenic and carcinogenic potential, has been studied extensively (Shabad et al 1974;Krivosheeval and Pylev 1974;Lakowicz and Bevan 1980;De Waele et al 1983a;Menard et al 1986aMenard et al , 1986bGerde and Scholander 1988;De Waele and Adams 1988). The chrysotile's adsorption of other polycyclic hydrocarbons (Menard et al 1986b;Craighead 1981, 1982;Fournier and Pezerat 1986), both aliphatic and aromatic amines (De Waele et al 1983a, 1983bDe Waele and Adams 1988;De Waele, Vansant, and Adams 1983), benzene (Gorski and Stettler 1975), and basic and acidic dyes -including picric acid (Valerio, Puntoni, and Santi 1979) -has also been investigated.…”