The Advances of Laparoscopic Gastrectomy for Gastric Cancer

Abstract

Laparoscopic gastrectomy is evolving. With the increasing expertise and experience of oncologic surgeons in the minimally invasive surgery for gastric cancer, the indication for laparoscopic gastrectomy is expanding to advanced cases. Many studies have demonstrated the benefits of minimally invasive surgery, including reduced risk of surgery-related injury, reduced blood loss, less pain, and earlier recovery. In order to establish concrete evidence for the suitability of minimal invasive surgery for gastric cancer, many multicenter RCTs, comparing the short- and long-term outcomes of laparoscopic versus open surgery, are in progress. Advances in laparoscopic gastrectomy are moving toward increasingly minimally invasive approaches that enable the improvement of the quality of life of patients, without compromising on oncologic safety.

Laparoscopic versus open gastrectomy for locally advanced gastric cancer: a systematic review and meta-analysis of randomized controlled studies

“…Almost a quarter of a century later, minimally invasive surgery for gastric cancer is being carried out more and more frequently in Asia and the Western world, though most experiences with minimally invasive surgery for gastric cancer come from Asia due to the higher disease incidence in this region. In Korea and Japan specifically, nationwide surveillance programs have played a role in the increased detection of gastric cancer at early stages [2], resulting in a substantial amount of experience with minimally invasive surgery for early gastric cancer. Several previous randomized controlled trials (RCTs) compared laparoscopic to open surgery for the treatment of early gastric cancer.…”

Laparoscopic D2 plus complete mesogastrium excision using the "enjoyable space" approach versus conventional D2 total gastrectomy for local advanced gastric cancer: short-term outcomes.

“…Laparoscopy-assisted D2 total gastrectomy for upper gastric cancer has undergone extensive development and gained popularity because of the advantages of minimally invasive surgery, including lower intraoperative blood loss, less postoperative pain, faster recovery, better cosmetic outcomes, fewer complications and more acceptable oncological out-comes than open gastrectomy [1][2][3][4]. However, locoregional recurrence often occurs in patients with local advanced gastric cancer (AGC), despite an R0 resection.…”

Proline-Rich Protein 11 Regulates Self-Renewal and Tumorigenicity of Gastric Cancer Stem Cells

“…Gastric carcinoma (GC) is the fourth most common malignancy worldwide [1]. Although there have been important medical advances in the diagnosis and treatment of GC over the past few decades, the survival rate remains low [1][2][3][4].…”

“…Although there have been important medical advances in the diagnosis and treatment of GC over the past few decades, the survival rate remains low [1][2][3][4]. Novel treatment strategies are urgently needed.…”