The Advancing Role of Nanocomposites in Cancer Diagnosis and Treatment

Andoh, Vivian; Ocansey, Dickson; Naveed, Hassan; Wang, Naijian; Chen, Liang; Chen, Keping; Mao, Fei

doi:10.2147/ijn.s471360

IJN

2024

DOI: 10.2147/ijn.s471360

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The Advancing Role of Nanocomposites in Cancer Diagnosis and Treatment

Vivian Andoh,

Dickson Ocansey,

Hassan Naveed

et al.

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2024

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Cited by 5 publications

References 171 publications

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Nanomedicine for cancer patient‐centered care

Sorrentino,

Ciummo,

Fieni

et al. 2024

MedComm

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Cancer is a leading cause of morbidity and mortality worldwide, and an increase in incidence is estimated in the next future, due to population aging, which requires the development of highly tolerable and low‐toxicity cancer treatment strategies. The use of nanotechnology to tailor treatments according to the genetic and immunophenotypic characteristics of a patient's tumor, and to allow its targeted release, can meet this need, improving the efficacy of treatment and minimizing side effects. Nanomedicine‐based approach for the diagnosis and treatment of cancer is a rapidly evolving field. Several nanoformulations are currently in clinical trials, and some have been approved and marketed. However, their large‐scale production and use are still hindered by an in‐depth debate involving ethics, intellectual property, safety and health concerns, technical issues, and costs. Here, we survey the key approaches, with specific reference to organ‐on chip technology, and cutting‐edge tools, such as CRISPR/Cas9 genome editing, through which nanosystems can meet the needs for personalized diagnostics and therapy in cancer patients. An update is provided on the nanopharmaceuticals approved and marketed for cancer therapy and those currently undergoing clinical trials. Finally, we discuss the emerging avenues in the field and the challenges to be overcome for the transfer of nano‐based precision oncology into clinical daily life.

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Nanomedicine for cancer patient‐centered care

Sorrentino,

Ciummo,

Fieni

et al. 2024

MedComm

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A Comprehensive Review of Recent Developments in Biomedical Materials Based on Graphene-Modified Bio-Nanocomposites

Pandey,

Nazar,

Elella

et al. 2024

BioNanoSci.

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Novel RGD-decorated micelles loaded with doxorubicin for targeted breast cancer chemotherapy

Tang,

Gao,

Liu

et al. 2024

Biomedicine & Pharmacotherapy

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The Advancing Role of Nanocomposites in Cancer Diagnosis and Treatment

Cited by 5 publications

References 171 publications

Nanomedicine for cancer patient‐centered care

Nanomedicine for cancer patient‐centered care

A Comprehensive Review of Recent Developments in Biomedical Materials Based on Graphene-Modified Bio-Nanocomposites

Novel RGD-decorated micelles loaded with doxorubicin for targeted breast cancer chemotherapy

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