The Advantages of Nanotechnology in Medical Field

Alshahrani, Abdullah

doi:10.17148/ijireeice.2016.4401

Cited by 3 publications

(3 citation statements)

References 33 publications

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“…Nanotechnology has been used in medicine, especially in the targeted treatment of cancer [10,11]. The advantages consist of the easily cross of cells barriers, control size and shape, increasing efficacy and reducing toxicity of anticancer drugs [12,13]. All these features, and more, have made nanotechnology the focus of attention [13].…”

Section: Nanotechnology In Cancer Treatmentmentioning

confidence: 99%

“…The high selectivity of NaCl nanoparticles is because the cancer cell contains more [Na+] than the normal cell and so it is exposed to more shock than the normal cell. In addition, the cancer cells have greater affinity for nanoparticles, and the dose needed to kill the tumor is much lower than the dose that affects the normal cell (Figure 1) [13,14]. NaCl nanoparticles are exploited as a novel type of cancer treatment which is taken up by cancer cells through endocytosis and release large amounts of ions inside them.…”

Section: Sodium Chloride Nanoparticles and Cancer (Scnps)mentioning

confidence: 99%

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Recent Methods in Cancer Treatment and Diagnosis

Shoujaa¹

2022

BJSTR

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Conventional cancer treatments and diagnosis, such as surgery, radiotherapy, chemotherapy, biopsy, and X-rays have been used for decades to detect cancer and to treat the patients who suffer from the malady symptoms, however the conventional cancer treatment is harmful to healthy cells, and the conventional cancer detection is not sufficiently sensitive, because it is possible only after substantial growth of cancerous cells. Novel strategies for the treatment and detection of cancer, such as Nanotechnology may greatly enhance the cure opportunities for patients and improve the quality of their life by minimizing the toxic effects of anticancer drugs. In the Nanotechnology methods, such as Sodium Chloride Nanoparticles (SCNPs), Liposomes, Magnetic Nanoparticle (MNPs), Quantum Dots (QDs), and Gold Nanoparticles (AuNPs), the nanoparticles can be designed and formulated to create therapeutic agents that targeting the cancerous cells. In this review, the details of these possi-ble detection, diagnosis and treatment methods of nanotechnology are discussed carefully.

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Section: Nanotechnology In Cancer Treatmentmentioning

confidence: 99%

Section: Sodium Chloride Nanoparticles and Cancer (Scnps)mentioning

confidence: 99%

Recent Methods in Cancer Treatment and Diagnosis

Shoujaa¹

2022

BJSTR

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“…Due to their small size, nanoparticles can enter the body and reach the specific tissue more efficiently and in a more direct fashion. Nanoparticles also have the capability to deliver molecules, such as from drugs, in less time and with lower pain to detect and cure diseases [2]. For nanomaterials to be used in the treatment of disease, many factors need to be considered, such as biodegradability, biocompatibility, size, hydrophilicity, and conjugation power with various drugs.…”

Section: Introductionmentioning

confidence: 99%

A Review of the Preparation, Characterization, and Applications of Chitosan Nanoparticles in Nanomedicine

Jha

Mayanovic

2023

Nanomaterials

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Chitosan is a fibrous compound derived from chitin, which is the second most abundant natural polysaccharide and is produced by crustaceans, including crabs, shrimps, and lobsters. Chitosan has all of the important medicinal properties, including biocompatibility, biodegradability, and hydrophilicity, and it is relatively nontoxic and cationic in nature. Chitosan nanoparticles are particularly useful due to their small size, providing a large surface-to-volume ratio, and physicochemical properties that may differ from that of their bulk counterparts; thus, chitosan nanoparticles (CNPs) are widely used in biomedical applications and, particularly, as contrast agents for medical imaging and as vehicles for drug and gene delivery into tumors. Because CNPs are formed from a natural biopolymer, they can readily be functionalized with drugs, RNA, DNA, and other molecules to target a desired result in vivo. Furthermore, chitosan is approved by the United States Food and Drug Administration as being Generally Recognized as Safe (GRAS). This paper reviews the structural characteristics and various synthesis methods used to produce chitosan nanoparticles and nanostructures, such as ionic gelation, microemulsion, polyelectrolyte complexing, emulsification solvent diffusion, and the reverse micellar method. Various characterization techniques and analyses are also discussed. In addition, we review drug delivery applications of chitosan nanoparticles, including for ocular, oral, pulmonary, nasal, and vaginal methodologies, and applications in cancer therapy and tissue engineering.

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