The age of vanadium-based nanozymes: Synthesis, catalytic mechanisms, regulation and biomedical applications

Li, Shuaiwen; Chen, Zihui; Yang, Feng; Yue, Wanqing

doi:10.1016/j.cclet.2023.108793

Cited by 7 publications

(2 citation statements)

References 87 publications

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“…Being a transition metal, vanadium has garnered significant attention owing to its potential applications in diverse fields, including medicine and catalysis . Nanomaterials derived from vanadium demonstrate the ability to replicate the functions of natural enzymes such as peroxidase, catalase, and superoxide dismutase. , These enzymes play a crucial role in combating oxidative stress , and cellular processes, making vanadium-based nanomaterials valuable for catalyzing various reactions.…”

Section: Metal Atom-based Nanozymes For Treatmentsmentioning

confidence: 99%

Single-Atom-Based Nanoenzyme in Tissue Repair

Fu,

Fan,

et al. 2024

ACS Nano

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Since the discovery of ferromagnetic nanoparticles Fe 3 O 4 that exhibit enzyme-like activity in 2007, the research on nanoenzymes has made significant progress. With the in-depth study of various nanoenzymes and the rapid development of related nanotechnology, nanoenzymes have emerged as a promising alternative to natural enzymes. Within nanozymes, there is a category of metal-based single-atom nanozymes that has been rapidly developed due to low cast, convenient preparation, long storage, less immunogenicity, and especially higher efficiency. More importantly, single-atom nanozymes possess the capacity to scavenge reactive oxygen species through various mechanisms, which is beneficial in the tissue repair process. Herein, this paper systemically highlights the types of metal single-atom nanozymes, their catalytic mechanisms, and their recent applications in tissue repair. The existing challenges are identified and the prospects of future research on nanozymes composed of metallic nanomaterials are proposed. We hope this review will illuminate the potential of singleatom nanozymes in tissue repair, encouraging their sequential clinical translation.

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Section: Metal Atom-based Nanozymes For Treatmentsmentioning

confidence: 99%

Single-Atom-Based Nanoenzyme in Tissue Repair

Fu,

Fan,

et al. 2024

ACS Nano

View full text Add to dashboard Cite

show abstract

“…In recent years, nanozymes have garnered significant attention within the biosensing community owing to their remarkable enzyme mimicry capabilities and their ability to address several shortcomings inherent in natural enzymes. − Generally speaking, nanozymes with mimicking activities of oxidase (OXD), laccase (LAC), and peroxidase (POD) are often used in the field of biosensing. − Among them, POD-like activity is most widely used in biosensing. However, the catalytic activity of most POD-like nanozymes reported in the past is limited to acidic solutions, which limits the development of nanozyme-based biosensors at neutral pH. − Although several reports have developed nanozymes with POD-like activity under neutral conditions, to the best of our knowledge, these nanozymes still have a significant loss of enzyme activity at neutral pH compared to which at its optimal pH. , Therefore, the development of nanozymes with optimal activity close to that at neutral pH still faces a great challenge.…”

Section: Introductionmentioning

confidence: 99%