The Aging Thyroid

Sawin, Clark T.

doi:10.1001/archinte.1985.00360080056006

Cited by 239 publications

(14 citation statements)

References 23 publications

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“…Among the total population studied the burden of thyroid disorder is 26 %, comprising of 20.7 % in females and 5.3 % in males. The proportion of thyroid disorder among age group of 21-50 is greater in females as compared to males and is also consistent with the finding of research workers, Sawin 28 , Gunter 29 , Ikem 30 and which is also supported in the literature. The proportion of hypothyroidism is more (6%) as compared to hyperthyroidism (3.4 %) in the study.…”

Section: Resultssupporting

confidence: 90%

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Untitled

2016

IJPSR

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Section: Resultssupporting

confidence: 90%

“…The proportion of hypothyroidism is more (6%) as compared to hyperthyroidism (3.4 %) in the study. The incidence of high proportion of hypothyroidism is also been reported by research workers 31,28,32 .…”

Section: Resultsmentioning

confidence: 60%

Untitled

2016

IJPSR

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“…По дан ным по пу ля ци он ных ис сле до ва-ний, рас про ст ра нен ность ма ни фе ст но го ги по ти ре о за в по пу ля ции со став ля ет 0,2-2% [1,2]. Рас про ст ра-нен ность суб кли ни че с ко го ги по ти ре о за зна чи тель но вы ше и ко леб лет ся в ши ро ком ди а па зо не: 4-10% в об щей по пу ля ции и 7-26% у по жи лых лю дей [3,4,5,6]. Ча с то та ги по ти ре о за вы ше у жен щин и воз ра с-та ет с уве ли че ни ем воз ра с та об сле ду е мых [3,7].…”

Section: вве де ниеunclassified

“…Соглас но ре зуль та там Фре мин гем ско го ис сле до ва-ния (1985 г. ), в ко то ром об сле до ва но 2139 че ло век (892 муж чи ны и 1256 жен щин) стар ше 60 лет, у 10,3% (5,7% муж чин и 13,6% жен щин) ре ги с т ри ро вал ся по-вы шен ный уро вень ти ре о т роп но го гор мо на (ТТГ) (>5 мМЕ/л) [6]. В по пу ля ци он ном ис сле до ва нии, вы пол нен ном в шта те Ко ло ра до (США) в 1995 г., по-вы шен ный уро вень ТТГ был вы яв лен у 9,5% из 25 862 об сле до ван ных при ме ди а не воз ра с та 56 лет [3].…”

Section: вве де ниеunclassified

Undiagosed hypothyroidism as risk factor of statin-induced rhabdomyolysis

et al. 2015

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Дислипидемия часто встречается у пациентов с гипотиреозом, в связи с чем встает вопрос о применении статинов в лече-нии. В то же время как гипотиреоз, так и прием статинов могут приводить к развитию миопатии и рабдомиолиза, что обусловливает озабоченность безопасностью применения этих препаратов у различных групп пациентов с гипотиреозом. Настоящая статья представляет собой обзор статей, клинических рекомендаций, инструкций к лекарственным препаратам, относящимся к проблеме назначения статинов у пациентов с гипотиреозом. На основании проанализированного материала даются рекомендации по применению статинов у пациентов с компенсированным и некомпенсированным гипотиреозом. Клю че вые сло ва: гипотиреоз, дислипидемия, статины, миопатия, рабдомиолиз.Dyslipidemia is a frequent condition in patients with hypothyroidism which determines possible need for statin use in treatement. However, both hypothyroidism and statin use can lead to myopathy and rhabdomyolysis so safety concerns are important for clinical decision. Current article is a review of publications, clinical guidelines and drug labels which are related to the problem of statin safety in patients with hypothyroidism. Recommendations are given for use of statin in patients with compensated and decompensated hypothyroidism based on review of data.

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“…The conclusion was that an elevated serum TSH level was a sensitive marker for thyroid deficiency in the elderly and was often the only way to detect it. 15 …”

Section: Prevalence Of Hyper and Hypothyroidismmentioning

confidence: 99%

Screening for thyroid disorders in asymptomatic adults from Brazilian populations

Benseñor

2002

Sao Paulo Med. J.

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Advances in thyroid disorder diagnosis have created new thyroid disorder categories such as subclinical hyperthyroidism and subclinical hypothyroidism. In the 1980s, immunometric assaying for thyroid stimulating hormone (TSH) emerged and became defined as the most cost-effective test in thyroid disorder screening. The second step in the screening of thyroid disorders is to determine free thyroxine (FT4), and cost-effective methods for its detection are now available. Using TSH and FT4, it is possible to determine four situations: clinical hyperthyroidism, clinical hypothyroidism, subclinical hyperthyroidism and subclinical hypothyroidism. Subclinical hypothyroidism can be a strong indicator of risk for atherosclerosis and myocardial infarction in elderly women. Cardiovascular mortality among Brazilian women is one of the highest in the Western world. The best-known risk factors for cardiovascular diseases are high blood pressure, smoking, diabetes, and hypercholesterolemia. Although these are recognized as primary risk factors, there are other risk factors that could be identified as primordial risk factors. This may be the case for subclinical hypothyroidism. Early detection of thyroid disorders in women over fifty could be a highly cost-effective option in the prevention of cardiovascular disorders among Brazilian women.

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The Aging Thyroid

Cited by 239 publications

References 23 publications

Untitled

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Undiagosed hypothyroidism as risk factor of statin-induced rhabdomyolysis

Screening for thyroid disorders in asymptomatic adults from Brazilian populations

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