The Allergen‐Glycerin Balance

Abstract

Poster Presentations P257 POSTERSincluded medial maxillectomy, image guidance, and intraoperative antibiotic irrigation. Postoperative management included nasal saline irrigation, dornase alfa inhalation, and serial antibiotic lavage. Most studies were limited to case reviews with relatively small numbers of patients. Very few randomized controlled studies were identified. Conclusion:Despite the prevalence of recurrent sinonasal disease after FESS in CF patients, sparse Level I data exists to support perioperative techniques that improve outcomes in this population. Most recommendations are based on small case series. Multicenter studies to evaluate perioperative strategies that improve FESS outcomes in CF patients are warranted. Results: A limited tolerance to elevated glycerin levels can prompt reductions in injection volume (and allergen dose) for patient safety and compliance. The IDT and MQT algorithms introduce a variety of allergen and glycerin levels to patient vials that can be difficult to monitor or calculate easily. Rhinology/Allergy Conclusion:The effectiveness and safety of subcutaneous immunotherapy is linked directly to patient tolerance of both allergen loads and glycerin levels. Convenient tools have been created to simplify calculation of final glycerin concentrations present in buildup and maintenance immunotherapy mixtures, and the final allergen doses.Rhinology/Allergy the "Mickey Mouse" Sign Jaiganesh Manickavasagam, MBBS, MRCS (presenter); Showkat Mirza; Saurabh SinhaObjective: In transnasal endoscopic pituitary surgery and transsellar approaches to anterior skull base lesions, a bony sella window is created with the lateral limits being the carotid arteries.Method: Coronal CT scan of the sphenoid sinuses were reviewed in a tertiary referral hospital and compared with intra operative findings.Results: Sphenoid anatomy is variable in terms of the degree of pneumatization and bony anatomy around the pituitary gland and internal carotid arteries. We describe a radiological sign ascertained from computerized tomography (CT) that when present indicates whether the carotid arteries can be readily identified endoscopically on entering the sphenoid sinus. On the axial CT the carotid arteries may produce protuberances either side of the sella which together with the bony sella and dorsum sella appear to form the outline of the head of Mickey Mouse or a teddy bear. Conclusion:When this sign is not present then the junction between the sella and carotids may not be clear and surgeons must be cautious or use neuronavigation. Rhinology/Allergy the Role of SEB on the Differentiation of t Cells in CRS Yong Min Kim, MD (presenter); Young-Hoon YoonObjective: Recent studies indicate that there is a subset of CD4+CD25+FoxP3+ T cells (Treg cells) that express interleukin (IL)-17 and the cells might be new proinflammatory cells because of the expression of IL-17. The aim of this study was to investigate the role of SEB on the differentiation of regulatory T cells to cells that express retinoic acid related or...