The Anæsthetist's Viewpoint on the Treatment of Respiratory Complications in Poliomyelitis during the Epidemic in Copenhagen, 1952

Ibsen, B

doi:10.1177/003591575404700120

Cited by 122 publications

(73 citation statements)

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“…Eventually the manual workforce comprised virtually all of Copenhagen's medical students, and later also dental students (2), and some nurses. Anaesthetists supervised their labours, and the patients received round-the-clock skilled nursing attention (7)(8)(9). The initial 3 months of this new system of treatment was estimated to have saved 100 lives (5).…”

Section: The Event (In Brief)mentioning

confidence: 99%

“…Lassen (4,5,10,11), Bjørn Ibsen (1,8,9,12) and Poul Astrup (3,13,14) are perhaps the bestknown names of those involved in these aspects of the epidemic. Others include Erik Wainø Andersen (7), Mogens Bjørneboe, Frits Neukirch, J. Pedersen, and T. Søttrup (4); but a magnificent team effort and organization of personnel (doctors, nurses, students and back-up) were essential to the ultimate success.…”

Section: The Event (In Brief)mentioning

confidence: 99%

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August 26th 1952 at Copenhagen: ‘Bjørn Ibsen's Day'; A significant event for Anaesthesia

Trubuhovich

2004

Acta Anaesthesiol Scand

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Section: The Event (In Brief)mentioning

confidence: 99%

Section: The Event (In Brief)mentioning

confidence: 99%

August 26th 1952 at Copenhagen: ‘Bjørn Ibsen's Day'; A significant event for Anaesthesia

Trubuhovich

2004

Acta Anaesthesiol Scand

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“…However, as a syndrome, ALI/ARDS has no specifi c treatment, only supportive care: treating the underlying cause when possible and using mechanical ventilation to ensure adequate gas exchange. During the 1952 polio epidemic in Copenhagen, mortality was reduced dramatically with the use of positive pressure ventilation; since then, mechanical ventilation has become the most common procedure in the management of critically ill patients, with more than half receiving mechanical ventilation immediately on admission to the intensive care unit [7,8].…”

Section: Introductionmentioning

confidence: 99%

Respirator management of sepsis-related respiratory failure

Chiumello

Cressoni²

2009

Curr Infect Dis Rep

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The first description of acute respiratory distress syndrome (ARDS) in adults appeared in 1967 and was characterized by dyspnea, hypoxemia, diffuse alveolar infiltrates, and reduced respiratory system compliance. ARDS and acute lung injury (ALI) syndrome have no specific treatment, only supportive care: treating the underlying cause, when possible, and using mechanical ventilation. Historically, mechanical ventilation applied normal/large tidal volumes and low levels of positive end-expiratory pressure (PEEP). Experimental data showed that a high-volume, high-pressure ventilation strategy may lead to lung lesions indistinguishable from ARDS. Subsequent randomized clinical trials showed improved survival using low tidal volumes (6 vs 12 mL/kg ideal body weight) and limiting plateau pressure to 30 cm H(2)O, although the optimal level of PEEP remains controversial. Prone positioning should be reserved for severely ill patients. Inhaled nitric oxide, which is a pulmonary vasodilator with anti-inflammatory properties, is associated with limited improvement in oxygenation without improvement in survival.

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“…The turning point was the realization that most deaths were due to inadequate ventilation [1,2]. This led to the birth of positive pressure ventilation, respiratory physiological monitoring and with it intensive care medicine.…”

mentioning

confidence: 99%

Deadspace ventilation: a waste of breath!

2011

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Problems with ventilatory efficiency results in abnormal CO(2) clearance. Measuring deadspace ventilation should be the most reliable method of monitoring ventilatory efficiency in mechanically ventilated patients. Since its first description by Bohr in the late 19th century to the current use of single-breath test for volumetric CO(2), our understanding of the physiological deadspace has vastly improved. Yet indices of oxygenation seem to be the mainstay when instigating or fine-tuning ventilatory strategies. Deadspace and with it ventilatory efficiency has been largely forgotten. Recently though there has been a resurgence of interest in ventilatory efficiency. Several indices have been described that either predict deadspace or track ventilatory efficiency at the bedside. Thus making it more accessible and easy to monitor and study in large groups of patients, factors which have perhaps resulted in its under-utilisation in critical care. This review revisits the physiological concepts and methods of measuring deadspace. Described are the various clinical applications of deadspace measurements in the critically unwell. The potential reasons that have led to the variable being under-used are also examined. Finally we describe the indices currently available to track ventilatory efficiency at the bedside.

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The Anæsthetist's Viewpoint on the Treatment of Respiratory Complications in Poliomyelitis during the Epidemic in Copenhagen, 1952

Cited by 122 publications

References 0 publications

August 26th 1952 at Copenhagen: ‘Bjørn Ibsen's Day'; A significant event for Anaesthesia

August 26th 1952 at Copenhagen: ‘Bjørn Ibsen's Day'; A significant event for Anaesthesia

Respirator management of sepsis-related respiratory failure

Deadspace ventilation: a waste of breath!

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