The Analgesic Effect of Paracetamol When Added to Lidocaine for Intravenous Regional Anesthesia

Şen, Hüseyin; Külahçi, Yalçın; Biçerer, Enis; Özkan, Sezai; Dağlı, Güner; Turan, Alparslan

doi:10.1213/ane.0b013e3181b0fedb

Cited by 42 publications

(41 citation statements)

References 16 publications

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“…In Yasser M et al study [9] using 100 mg tramadol with 3 mg/kg 0.5% lidocaine in IVRA showed significantly early onset time and delayed recovery time of sensory and motor block than lignocaine group. In Sen et al [10] study on addition of paracetamol to lignocaine 3 mg/kg in IVRA lead to early onset of motor block and delayed offset of sensory and motor block than lignocaine group. Our results were in accordance with results of these studies.…”

Section: Discussionmentioning

confidence: 97%

Comparison of the Effects of Lignocaine, Lignocaine Plus Paracetamol, Lignocaine Plus Tramadol in Intravenous Regional Anesthesia

Kataria¹,

Kaur²,

Bala³

et al. 2015

jemds

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INTRODUCTION:Intravenous regional anesthesia is simple, effective technique for upper limb orthopedic surgeries however adjuncts are required to improve its efficacy. AIMS: To compare the effects of adding paracetamol and tramadol as adjunct to lignocaine in intravenous regional anesthesia on onset and regression of sensory and motor blockage, analgesic requirements, duration of analgesia and side effects. PATIENTS AND METHOD: A randomized study was carried out on ninety patients who were undergoing upper limb orthopedic surgery, divided in to three groups: group I (L) received 3mg/kg lignocaine 0.5% diluted up to 40 ml with normal saline, group II (LP) received 3mg/kg lignocaine 0.5% with 300mg paracetamol diluted up to 40 ml with normal saline, group III (LT) received 3mg/kg lignocaine 0.5% with tramadol 100mg diluted up to 40 ml with normal saline. Sensory and motor block onset, regression time, intraoperatively and postoperatively VAS score, duration of analgesia, total analgesic consumption in first 24 hr and side effects noted. Analysis of data based on chi square test and post hoc test. P value < 0.05 considered significant. RESULTS: A total of ninety patients were included in study. The mean age of patients in group I was 32.60±14.8 years, in group II was41.67±16.6 years while in group III was 38.73±13.3 years. Tramadol with lignocaine was found to be significantly better as compared to paracetamol and lignocaine alone had early onset and delayed offset of sensory and motor block. The tramadol group required significantly less number of rescue analgesics in first 24 hours as compared to the other two groups. CONCLUSION: We concluded that as adjuvant tramadol group was accompanied by more rapid onset, longer duration of analgesia provides better quality of anesthesia and lesser number of patients require rescue analgesia intraoperatively as well as postoperatively without any significant side effects.

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Section: Discussionmentioning

confidence: 97%

Comparison of the Effects of Lignocaine, Lignocaine Plus Paracetamol, Lignocaine Plus Tramadol in Intravenous Regional Anesthesia

Kataria¹,

Kaur²,

Bala³

et al. 2015

jemds

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“…It has some advantages for example providing a blood-free surgery site, an easy applicability, a rapid termination of the anesthetic effect when compared with general anesthesia. Some clinical studies demonstrated that the addition of analgesics to the local anesthetics during IVRA decreased tourniquet pain and increased anesthesia quality in hand and forearm surgeries [10][11][12].…”

Section: Hand and Forearm Surgerymentioning

confidence: 99%

Regional Anesthesia Techniques in Orthopedic Surgery

Eroğlu¹

2016

JACCOA

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Background: The effect of regional anesthesia techniques on orthopedic surgeries is very actual topic in current clinical practice. Aim:The aim of this review article was to research regional anesthesia techniques for postoperative pain control and outcomes in orthopedic surgeries. Methods:The English literature was reviewed based on a search regional anesthesia and orthopedic surgery in clinical studies.Major findings: A number of authors proposed that regional anesthesia in orthopedic patients may be associated with better postoperative pain control and a reduction in intraoperative blood loss when compared with general anesthesia. Conclusion:In the future regional anesthesia techniques will be more preferable anesthetic technique in orthopedic surgeries.

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“…10 Two control groups, one for IVRA injectate (lidocaine only) and a second for paracetamol administered systemically, were used. The authors found that the addition of paracetamol to the IVRA injectate significantly reduced patients' intraoperative pain at 20 and 30 minutes compared with control groups (p ϭ .018 and p ϭ .03, respectively).…”

Section: Pharmacologic Considerationsmentioning

confidence: 99%

Why Do Bier Blocks Work for Hand Surgery … Most of the Time?

Blackburn¹,

Shafritz²

2010

The Journal of Hand Surgery

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The Analgesic Effect of Paracetamol When Added to Lidocaine for Intravenous Regional Anesthesia

Abstract: The addition of paracetamol during IVRA with lidocaine decreased tourniquet pain, increased anesthesia quality, and decreased postoperative analgesic consumption.

Cited by 42 publications

References 16 publications

Comparison of the Effects of Lignocaine, Lignocaine Plus Paracetamol, Lignocaine Plus Tramadol in Intravenous Regional Anesthesia

Comparison of the Effects of Lignocaine, Lignocaine Plus Paracetamol, Lignocaine Plus Tramadol in Intravenous Regional Anesthesia

Regional Anesthesia Techniques in Orthopedic Surgery

Why Do Bier Blocks Work for Hand Surgery … Most of the Time?

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