Spatial mechanisms of various types are widely used in technology. Most of them have one or two ball pairs, the presence of which reduces the service life of the device (ball pairs are difficult to protect from dust and dirt. They are more difficult to manufacture and have a lower loadbearing capacity than rotational pairs). Replacing ball pairs with rotary ones, designed, for example, with standard bearings, will greatly simplify and reduce the cost of their manufacturing technology, increase the service life and expand the area of practical application. The difficulty and complexity of creating fivelink and six-link mechanisms and devices with a special structure lies in the fact that the usual combination of links fails to achieve their operability (with rotatable links). Theoretically, this mechanism has been studied by many foreign and Russian scientists. However, Kazan scientists were the first to form and put into practice spatial mechanisms with rotational pairs. The paper presents synthesis and analysis of the spatial five-link mechanism by the degree of irregularity, axial displacement, elliptical law and by the reproduction of a linear function. The mechanism provides intensification and energy saving of mixing, separation, torque transmission of various drives.