This study investigates the effectiveness of different ventilation methods in reducing indoor air pollutants in newly constructed residential buildings, focusing on indoor air quality (IAQ) in Dubai. The paper highlights the growing concern for IAQ in response to residents’ increasing awareness of their well-being and environmental sustainability. The study examines the concentrations of formaldehyde (HCHO), volatile organic compounds (VOCs), and total volatile organic compounds (TVOC) in bedrooms and living rooms before and after implementing various ventilation methods during the construction phase. The findings indicate that mechanical exhaust ventilation, mainly through bathroom and kitchen exhaust fans, was highly effective in reducing HCHO levels. Combining kitchen and bathroom exhaust fans demonstrated the most significant reduction in HCHO concentrations. Similarly, reductions in VOCs, such as ethylbenzene, toluene, and xylene, were observed with different ventilation methods. Natural ventilation also proved effective in reducing pollutant concentrations. The results emphasize the importance of implementing appropriate ventilation strategies to improve IAQ in residential buildings. However, the study acknowledges the limitations of a single-location measurement and recommends further research to validate the findings across different building types and locations. Additionally, long-term studies are necessary to assess the sustained effects of ventilation methods on IAQ. The study highlights the significance of addressing IAQ concerns in residential buildings and suggests potential research directions to explore other ventilation strategies and their energy efficiency implications. Ultimately, this research contributes to developing healthier and sustainable living environments by promoting effective ventilation strategies to mitigate indoor air pollutants.