The analysis of related factors of ventricular aneurysm formation in patients with acute myocardial infarction in northwest of China

Pang, Junxiong; Zhang, Zheng; Zheng, Tongzhang; Bassig, Bryan A.; Ge, Junbo; Yang, Yuejin; Bai, Ming; Yu, Peng

doi:10.1016/j.ijcard.2014.12.010

Cited by 3 publications

(3 citation statements)

References 23 publications

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“…[14,15] The ventricular aneurysms were diagnosed according to the electrocardiogram, left ventriculography, magnetic resonance imaging (MRI), or transthoracic echocardiography. [16] …”

Section: Methodsmentioning

confidence: 99%

Aneurysm-related ischemic ventricular tachycardia

Guo

Zheng²,

Wu³

et al. 2017

Medicine

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Left ventricular aneurysm (LVA) postmyocardial infarction (MI) might be an arrhythmogenic substrate. We examined the safety and efficacy of catheter ablation of LVA-related ventricular tachycardia (VT).Thirty-three consecutive patients who underwent primary catheter ablation of ischemic VT were divided into LVA group (11 patients, mean age 61.9 years, 10 men) and none LVA group. Acute procedural outcomes, complications, and long-term outcomes were assessed.In LVA group, average number of induced VTs were 3.2 ± 2.6 (range 1–7), clinical VTs were located in the ventricular septum scar zone in 4 (36.4%) patients, acute success was achieved in 7 (63.6%) patients, partial success in 3 (27.3%) and failure in 1 patient, while none LVA group showing a statistically similar distribution of acute procedural outcomes (P = 0.52). There were no major or life-threatening complications. VT-free survival rate at median 19 (1–44) months follow-up was numerically but not significantly lower in LVA versus none LVA group (48.5% vs 62.8%, log-rank P = 0.40).Catheter ablation of ischemic VT in the presence of LVA appears feasible and effective, with about one-third of cases having septal ablation targets. Further studies are warranted.

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“…[14,15] The ventricular aneurysms were diagnosed according to the electrocardiogram, left ventriculography, magnetic resonance imaging (MRI), or transthoracic echocardiography. [16] …”

Section: Methodsmentioning

confidence: 99%

Aneurysm-related ischemic ventricular tachycardia

Guo

Zheng²,

Wu³

et al. 2017

Medicine

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“…It is a serious sequela of left ventricular remodeling caused by AMI and is related to deteriorative clinical outcomes (1). Previous studies showed that the incidences of LAD artery stenosis in LVA and non-LVA were 89.6% and 69.6%, respectively (16). Given that the LAD artery provides the major blood supply for the anterior wall while not easily forming collateral circulation, it is prone to LVA formation after acute anterior myocardial infarction.…”

Section: Incidence and Predictors Of Lvamentioning

confidence: 99%

“…Given that the LAD artery provides the major blood supply for the anterior wall while not easily forming collateral circulation, it is prone to LVA formation after acute anterior myocardial infarction. However, most of the previous reports were based on the entire myocardial infarction population (16)(17)(18)(19). To avoid biases, this study focused on LVA formation due to acute anterior myocardial infarction, the data of which are limited in the contemporary PCI era.…”

Section: Incidence and Predictors Of Lvamentioning

confidence: 99%

Predictors and long-term prognosis of left ventricular aneurysm in patients with acute anterior myocardial infarction treated with primary percutaneous coronary intervention in the contemporary era

You¹,

Gao²,

Shen³

et al. 2021

J Thorac Dis

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Background: Primary percutaneous coronary intervention (PCI) has been the standard reperfusion strategy for patients with acute myocardial infarction (AMI) in the contemporary era. Meanwhile, the incidence and prognosis of left ventricular aneurysm (LVA) in AMI patients remain ambiguous. The aim of the current study is to identify the predictor and long-term prognosis of LVA in patients with acute anterior myocardial infarction. Methods: We prospectively enrolled 942 consecutive patients with acute anterior myocardial infarction who were treated by primary PCI. The baseline characteristics, procedural features, and one-year clinical outcomes were compared between the patients with and without LVA. The primary endpoint of major adverse cardiovascular and cerebrovascular events (MACCEs) was defined as a composite of cardiac death, target vessel revascularization, and ischemic stroke. Multiple logistic regression was applied to predict LVA formation and the receiver operating characteristic (ROC) curves were plotted to evaluate the accuracy of the multivariate analysis model. Results: The general incidence of LVA was 15.92%. At one-year clinical follow-up, patients in the LVA group had significantly higher incidence of MACCEs (15.33% vs. 6.44%, P<0.01), mainly driven by an increased incidence of cardiac death (8.00% vs. 2.78%, P<0.01), target vessel revascularization (5.33% vs.2.27%, P=0.03), and ischemic stroke (4.00% vs. 1.39%, P=0.03). Multivariate analysis found that longer symptom-to-balloon time (S2B) [

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