While casting may have historically been used to make components with free-form surfaces, five-axis milling with ball end cutters is becoming increasingly common. Although this form of production enables the use of more robust billet material rather than cast material, it generates identifiable machining cusps on the component's surface. This paper investigates the use of the Theory of Critical Distances (TCD) to predict the fatigue life of five-axis machined components. TCD's Point Method (PM) and Line Method (LM) have been adapted to treat the machining cusps as stress raisers. This has been incorporated with the Medium Cycle Fatigue (MCF) procedure of TCD to predict the life of specimens machined with distinct tool sizes. The predictions obtained were found to be conservative.