The Analysis of Surgical Outcomes in Operable Gastric Cancer Patients Presenting With or Without Sarcopenia

Bhattacharyya, Supratim; Devi, Padmalaya; Das, Prafulla Kumar; Samantara, Subrat; Mohammed, K P Kunhi; Pradhan, Snehasis; NK, Muhammed Navas

doi:10.1007/s13193-022-01514-w

Cited by 2 publications

(1 citation statement)

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“…We hypothesized that patients with presarcopenia did not compromise the clinical and oncological outcomes of laparoscopic surgery for rectal cancer. Bhattacharyya et al [ 22 ] compared clinical outcomes after gastric cancer surgery between the sarcopenia and nonsarcopenia groups. They demonstrated that delayed passage of first flatus and postoperative complications are high in sarcopenic patients and concluded that sarcopenia is an independent prognostic factor for adverse short-term outcomes in patients with gastric cancer after curative intent resection.…”

Section: Discussionmentioning

confidence: 99%

Computed tomography–assessed presarcopenia and clinical outcomes after laparoscopic surgery for rectal cancer

Song,

Oh,

Lee

et al. 2023

Ann Coloproctol

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Purpose: Previous studies have reported that presarcopenia negatively affects rectal cancer treatment. However, most studies have analyzed patients including majority of open surgery, and the association between presarcopenia and clinical outcomes after laparoscopic rectal cancer surgery remains unclear. This study aimed to evaluate the impact of presarcopenia on the clinical and oncological outcomes after laparoscopic rectal cancer surgery.Methods: Three hundred and one patients undergoing laparoscopic rectal cancer surgery between December 2009 and May 2016 were enrolled. Body composition was assessed using computed tomography by measuring the muscle and fat areas at the third lumbar (L3) vertebra. The L3 skeletal muscle area was used to calculate the skeletal muscle index and evaluate presarcopenia.Results: Presarcopenia was more common in older ( ≥ 70 years, P = 0.008) or female patients (P = 0.045). Patients with presarcopenia had decreased skeletal muscle area (P < 0.001), lower hemoglobin level (P = 0.034), longer time to first flatus (P < 0.001), and more frequent surgical site infection (P = 0.001). However, survival rates were not significantly different between those with and without presarcopenia.Conclusion: Computed tomography-assessed presarcopenia was associated with delayed functional recovery and increased surgical site infection, although it was not revealed as a prognostic factor for oncological outcomes.

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Section: Discussionmentioning

confidence: 99%