Abstract. The Venice lagoon (Italy) is particularly vulnerable to the impact of subsidence and sea level rise driven by climate change. Some structural
measures have been adopted over time to protect Venice from flooding, among which a system of flap gates (Experimental Electromechanical Module, Mo.S.E., system) has been operational in the
testing phase since October 2020. However, relative sea level rise and wind set-up pose relevant management challenges, as a frequent closing of the
lagoon would have negative impacts on flushing capacity, the fishing industry, and port activities. Here, the focus is on the hydrodynamic effects of a
partial closure of the Mo.S.E. barriers that, compared to closing all the three inlets of the lagoon, could play a role in reducing the economic and
environmental impacts of the Mo.S.E. system. The main goal is to identify the flooding events that can be counteracted by closing only the Lido
inlet, which is the closest to the city of Venice. Based on the tidal and meteorological dataset collected in the period 2000–2019, a robust
modelling exercise identifies a linear relationship between tidal range and reduction of the sea level peaks, which results in the protection of all
urban settlements within the lagoon from two-thirds of the flooding events up to a relative sea level rise of +0.4 m.