2012
DOI: 10.5539/jas.v4n9p196
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The Anti-brain Ageing Effects of Krill Phosphatidylserine in SAMP10 Mice

Abstract: We examined the biological effect of krill phosphatidylserine (K-PS) on brain ageing and investigated the mechanisms that how K-PS works on the brain using senescence-accelerated mouse (SAM) model with age-associated neurodegeneration. SAMP10 mice with 5 months of age were treated orally once a day for 75 days with 10 or 100 mg kg −1 d −1 K-PS (low and high dose). The effect of K-PS treatment on the cross-sectional area and Nissl body number of the neocortex at point C, an area prone to atrophy in SAMP10 mice,… Show more

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“…Immunohistochemistry staining was performed as described previously (Wang et al 2012). Briefly, the sections were deparaffinized with xylene and rehydrated in graded alcohols.…”
Section: Immunohistochemistrymentioning
confidence: 99%
“…Immunohistochemistry staining was performed as described previously (Wang et al 2012). Briefly, the sections were deparaffinized with xylene and rehydrated in graded alcohols.…”
Section: Immunohistochemistrymentioning
confidence: 99%