“…Boros et al (2012) demonstrated that the inhalation of 2.5% CH 4 significantly ameliorated the extent of ischaemiaereperfusion damage that can induce oxidative and nitrosative stress in dogs. A parallel series of experiments showed that exogenous CH 4 inhibited leucocyte infiltration in vitro, demonstrating Kirschke et al (2013) for topdown estimates encompassing 2000e2009.…”
Section: Uncertainties and Limitationsmentioning
confidence: 99%
“…2 of Kirschke et al (2013). the connection between CH 4 function and the immune system (Boros et al, 2012). The effects of exogenous CH 4 on animal pathophysiology indicate the possibility of endogenous CH 4 production.…”
“…Boros et al (2012) demonstrated that the inhalation of 2.5% CH 4 significantly ameliorated the extent of ischaemiaereperfusion damage that can induce oxidative and nitrosative stress in dogs. A parallel series of experiments showed that exogenous CH 4 inhibited leucocyte infiltration in vitro, demonstrating Kirschke et al (2013) for topdown estimates encompassing 2000e2009.…”
Section: Uncertainties and Limitationsmentioning
confidence: 99%
“…2 of Kirschke et al (2013). the connection between CH 4 function and the immune system (Boros et al, 2012). The effects of exogenous CH 4 on animal pathophysiology indicate the possibility of endogenous CH 4 production.…”
“…Az emésztőrendszerbeli képződés mellett, egyre több publikáció támasztja alá a kilélegzett (vagy növények esetén kibocsátott) metánkoncentráció és az oxido-reduktív stressz kapcsolatát [76,83]. A témával kapcsolatban jelentős eredményeket értek el a Szegedi Tudományegyetem Sebészeti és Műtéttani Intézetének kutatói is [84][85][86].…”
“…Much attention has recently been paid to the bioactivity of CH 4 An anti-inflammatory potential for CH 4 was first reported by Boros and colleagues in experimental mesenteric IR (Boros et al, 2012). Over the past few years many other papers have been published on the anti-inflammatory effects of CH 4 in various animal models of IR, hypoxia and sterile inflammation (see Table 2).…”
Section: Biological Effectsmentioning
confidence: 99%
“…Red blood cells contribute to 40-50% of the total volume of the circulating blood; therefore erythrocyte lipid membranes are good candidates to carry the gas. Also, it has been shown that in this concentration range, CH 4 in the inhaled air has no measurable impact on O 2 delivery and saturation (Boros et al, 2012).…”
Section: The Kinetics Of Ch 4 Transport In Vivomentioning
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