The Antibacterial Activity of SnO2 Nanoparticles against Escherichia coli and Staphylococcus aureus

Abstract

Background: An increasing amount of populations all over the world are reported to have no access to clean and fresh water. Some traditional chemical disinfectants (free chlorine, chloramines, and ozone) are already widely used in the water industry; alarmingly, many of these are carcinogens. Furthermore, the resistance of microorganisms to these common chemical disinfectants is increasing; superior alternatives are therefore necessary. The development of nanoscience and nanotechnology within the last decades provides opportunities to deal with this problem. Objectives: In this study, the solvothermal method was employed to synthesize SnO 2 nanoparticles with spherical morphology in the absence of templates or structure-directing agents under mild conditions. The nanoparticles used to in the inactivation efficiencies for two microorganisms under UV irradiation and dark conditions. Materials and Methods: In this experimental study, tin dioxide (SnO 2) nanoparticles have been synthesized via a simple solvothermal method in the absence of templates or structure-directing agents under mild conditions. The prepared SnO 2 sample was employed for the inactivation of Gram-negative Escherichia coli (ATCC 25922) and Gram-positive Staphylococcus aureus (ATCC 29213) in MilliQ water under dark and UV illumination. The antibacterial activity of the synthesized SnO2 nanoparticles was evaluated using bacterium as per colony count method. Results: SnO 2 nanoparticles were successfully synthesized via solvothermal method under mild condition. SEM image showed SnO 2 nanoparticles were spherical when a mixture of water and ethanol used as solvent. The prepared SnO 2 nanoparticles were employed for the inactivation of gram-negative Escherichia coli (ATCC 25922) and gram-positive S.aureus (ATCC 29213) in MilliQ water. It was found that SnO 2 nanoparticles show much higher activity against E. coli than S.aureus. Conclusions: According to the result of this study, SnO 2 nanoparticles are an excellent antibacterial agent for bactericidal applications.

Biogenesis, Characterization and Bioefficacy of Tin Oxide Nanoparticles from Averrhoa Bilimbi Fruit Extract

“…The above data guarantees with the previous research which has been conducted with the SnO 2 nanoparticles studies [38]. Nanoparticles exerts its anti-microbial activity by breaking the cell wall membrane and thereby causing disturbance in the cell functioning [44]. Previously, studies have reported that tin oxide nanoparticles possess significant antimicrobial activity [18].…”

“…The zone of inhibition was measured in mm and was found to be 35 mm for calcinated SnO 2 nanoparticles against Klebsiella and 18mm for the same against S. aureus (Table III). The lower concentration of nanoparticles didn't give much promising result against the microbes [33], [34].…”

Biocompatible Tin Oxide Nanoparticles: Synthesis, Antibacterial, Anticandidal and Cytotoxic Activities

“…Kumar 2017, also reported that SnO 2 NPs, bind to the outer membrane, thereby inhibiting the growth of Pseudomonas and Staphylococcus aureus, which goes in agreement with the studies conducted by Raj et al. and Amininezhad et al ,…”

Electrochemically assisted photocatalysis: Highly efficient treatment using thermal titanium oxides doped and non-doped electrodes for water disinfection

“…In gram-negative bacteria E. coli, the plasma membrane is surrounded by a cell wall composed of peptideoglycan, followed by an outer membrane of proteins, lipids and lipopolysaccharides. Its structure is often thinner than the cell wall of gram-positive bacteria S. aureus (Feng Amininezhad et al (2015). According to Rinc on and Pulgarin (2004), certain bacteria, especially gram-positive, have a very viscous capsule, which functions as a protection to the cellular wall.…”