The Antibacterial Effectivity of Ethanol Extract of Red Grape (Vitis vinifera Variant Red globe) as a Root Canal Irrigation Material Against the Growth of Actinomyces spp. Bacteria in Vitro

Abstract

Actinomyces spp. is a bacterium that can cause root canal failure. Many antibacterial materials have been used to kill Actinomyces spp., especially natural materials for developing dentistry green economics. One is grapes (Vitis vinifera variant Red globe) because they have active antibacterial compounds, flavonoids, phenolic acids, and tannins. This study aims to determine the antibacterial effectivity of ethanol extract of red grapes (Vitis vinifera variant Red globe) as a root canal irrigation material against the growth of Actinomyces spp. bacteria in vitro. This study used a true experimental research using the dilution methods with 8 sample groups, consisting of K(-), K(+), 25%, 22,5%, 20%, 17,5%, 15%, dan 12,5%. Kruskal Wallis was statistical analysis tested to determine the significance of differences in the treatment group. Minimum Bactericidal Concentration (MBC) at a concentration of 15%. Statistical tests showed significant differences in the effect of ethanol extract of red grapes (Vitis vinifera variant Red globe) at each concentration in inhibiting the growth of Actinomyces spp. bacteria. In this study, the ethanolic extract of red grapes (Vitis vinifera variant Red globe) has antibacterial effectivity as a root canal irrigation material against the growth of Actinomyces spp. bacteria in vitro.