The Antibacterial Evaluation of Moringa Oleifera Leaf Extracts on Selected Bacterial Pathogens

Abalaka, M. E.; Daniyan, S. Y.; Oyeleke, S. B.; Adeyemo, S. O.

doi:10.5923/j.microbiology.20120202.01

Cited by 82 publications

(71 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Bukar et al (2010) and Suarez et al (2003) identified, the presence of a short polypeptide named 4 (α-Lrhamnosyloxy) benzyl-isothiocyanate in moringa seeds. The peptide might act directly on microorganisms and might result in growth inhibition by destroying the cell membrane (Abalaka et al, 2012 Asokkumar et al (2009). This is in accordance with previous discovery that suggested the flavonoids carry antioxidant activity through scavenging or chelating have deterrent role in cancer and heart disease (Middleton et al, 2000).…”

Section: Effect Of Extraction Methods On Nutritional and Anti -Nutritsupporting

confidence: 76%

“…Whereas, it showed less effective against E. coli and P. aeruginosa. This suggested that, the SC-CO 2 extracted moringa seed kernel extract might be used for treatment of infections caused by these organisms except E. coli and P. aeruginosa, which were found to be resistant to the activity of the SC-CO 2 extracted moringa seed kernel extract (Abalaka et al, 2012). The antimicrobial activity of M. oleifera seed extract might be due to the presence of an phytochemicals.…”

Section: Effect Of Extraction Methods On Nutritional and Anti -Nutritmentioning

confidence: 99%

See 1 more Smart Citation

Effect of extraction methods on physicochemical, nutritional, antinutritional, antioxidant and antimicrobial activity of Moringa (Moringa oleifera Lam.) seed kernel oil

Dinesha

Nidoni

Ramachandra

et al. 2018

JANS

View full text Add to dashboard Cite

Abstract:The effect of three different extraction methods, namely supercritical CO 2 , soxhlet and solvent methods on the yield, efficiency, physico-chemical properties, nutritional, anti-nutritional composition, antimicrobial and antioxidant activities of moringa (Moringa oleifera Lam.) seed kernel oil was investigated in this study. Oil extraction for SC-CO 2 were 37.76 g/100g and 98.43%, observed to be higher than those of soxhlet extraction (29.12 g/100g and 76.29%), and significantly lower than solvent extraction (22.12 g/100g and 57.99%). The physico-chemical composition of the oils showed considerable variation among the extraction methods. The SC-CO 2 extracted oil was found to be of superior quality, showing negligible thermal degradation and exhibited significantly (p<0.01) higher nutritional and antioxidant activity and lower anti-nutritional composition than the soxhlet and solvent extracted oils. Oils produced by SC-CO 2 and soxhlet extraction methods had antimicrobial activities higher than solvent extracted oil. SC-CO 2 extracted oil was found to have maximum number of bioactive compounds (14 compounds) followed by solvent (8 compounds) and soxhlet (4 compounds) extracted oil. The results of the study demonstrated that SC-CO 2 would be a promising process for the extraction of moringa seed kernel oil of premium quality.

show abstract

Section: Effect Of Extraction Methods On Nutritional and Anti -Nutritsupporting

confidence: 76%

Section: Effect Of Extraction Methods On Nutritional and Anti -Nutritmentioning

confidence: 99%

Effect of extraction methods on physicochemical, nutritional, antinutritional, antioxidant and antimicrobial activity of Moringa (Moringa oleifera Lam.) seed kernel oil

Dinesha

Nidoni

Ramachandra

et al. 2018

JANS

View full text Add to dashboard Cite

show abstract

“…Both were resistant to the entire organism at doses below 200mg/kg. Data from the ethanol was more sensitive at 200mg/kg and above than the aqueous extract as the aqueous was only sensitive to E. coli above this dose while K. aerogenes was resistant at all doses to the ethanol extract which is in agreement with the work done by Abalaka et al [5] and Karthic et al [6] where crude extracts shows a remarkable activity against the growth of E. coli, Salmonella and Pseudomonas.. The aqueous extract was resistant to all the organisms tested except E. coli.…”

Section: Discussionsupporting

confidence: 82%

Antibacterial, Haematological Parameters and Phytochemical Analysis of the Leaf Extracts of Moringa Oleifera

Olaniran¹

2016

ICPJL

View full text Add to dashboard Cite

Antimicrobial resistance has become a global problem and Strategies to improve the current situation necessitate finding new and innovative antimicrobial agents. Forty apparently healthy albino mice of either sex, weighing between 19kg and 27kg, aged 2 to 3 weeks were purchased and the various concentration of the extracts from Moringa oleifera leaves were given orally to the mice, the highest mean PCV was recorded in 800mg (33.0±1.22), White blood cell count 400mg (3,725±923.20), Neutrophil count 100mg (24.8±7±.65) and lymphocytes count 400mg (87.5±1.85), ethanol extracts had PCV to be highest in 200mg, White Blood Cell WBC 100mg (14,000±9453.4), neutrophils count 400mg(12.8±2.02) and lymphocytes count 800mg (91.5±2.22), the antimicrobial activity of the extracts on clinical isolates showed that the water extract 800mg/ml had the highest zone of inhibition of 6mm on the Escherichia coli, 19mm against Staphylococcus aureus, 18mm against Proteus mirabilis and 14mm against Escherichia coli, the ethanol extracts 800mg/ml had the highest zone of inhibition of 8mm against Salmonella typhii. 6mm against E.coli and S.aureus and 5mm against P.mirabilis, The phytochemical screening showed that both water and ethanol extracts had Flavonoid, Tannin, Glycoside, Terpenoid and Saponin with the absence of alkaloids in water, while reducing sugar was absent in both with Terpenoid having the highest concentrations in ethanol extracts 12.95mg/g and water extracts10.30mg/g.

show abstract

“…Further work is needed to carry out more pharmacological from the extracts in order to support antimicrobial activity of the M. oleifera. Our study demonstrated that folk medicine can be as effective as modern medicine to combat pathogenic microorganisms to carry out more pharmacological studies to support the use of M. oleifera as a medicinal plant [31].…”

Section: Resultsmentioning

confidence: 99%

Phytochemical and Antibacterial Activity of Moringa Oleifera Available in the Market of Mekelle

Amabye¹

2016

JAPLR

View full text Add to dashboard Cite

The aim of the present study was to evaluate the antibacterial activity of Moringa oleifera leaf extracts, Escherichia coli, Pseudomonas aeroginosa, Staphylococcus aureus, Proteus vulgaris, Streptococcus mutans, Bacillus subtilus, and Staphylococcus epidermidis bacteria were used. Phytochemical analyses of the leaf in solvents of varying polarity with aqueous, ethanol were also carried out. The phytochemical screening indicated the presence of flavonoids, tannins, steroid, alkaloid, saponins etc., in the both extracts. Well diffusion method was used to assess the antibacterial effect of the extracts on micro-organisms. The ethanolic and aqueous extract were active against all strains but the ethanol leaf extract showed maximum activity against Streptococcus mutant and aqueous extract shows maximum activity against Proteus vulgaris. The research showed that the higher reducing power of the aqueous extract could be due to the better solubility of the antioxidant components in water whereas the predominant antibacterial activity in organic solvent extracts as compared to aqueous extracts, indicates that the active components responsible for the bactericidal activity are more soluble in organic solvents. These studies provide an evidence to support traditional medicinal uses of the plant.

show abstract

The Antibacterial Evaluation of Moringa Oleifera Leaf Extracts on Selected Bacterial Pathogens

Cited by 82 publications

References 10 publications

Effect of extraction methods on physicochemical, nutritional, antinutritional, antioxidant and antimicrobial activity of Moringa (Moringa oleifera Lam.) seed kernel oil

Effect of extraction methods on physicochemical, nutritional, antinutritional, antioxidant and antimicrobial activity of Moringa (Moringa oleifera Lam.) seed kernel oil

Antibacterial, Haematological Parameters and Phytochemical Analysis of the Leaf Extracts of Moringa Oleifera

Phytochemical and Antibacterial Activity of Moringa Oleifera Available in the Market of Mekelle

Contact Info

Product

Resources

About