The Antioxidant and Antibacterial Activities of the Essential Oils of <i>Marrubium vulgare</i> Growing Wild in Eastern Algeria

Abstract

The chemical composition was analyzed by gas chromatography (GC) and gas chromatography/mass spectrometry (GC/MS). The constituents were identified by their mass spectra and Kovats' indices. Fivety (50) components in the oil of M. vulgare were identified. The results demonstrated that the major components of the essential oil were : 4,8,12,16-Tetramethyl heptadecan-4-olid (16.97 %), Germacrene D-4-ol (9.61 %), α-pinéne (9.37 %), Phytol (4.87 %), Dehydro-sabina ketone (4.12 %), Piperitone (3.27 %), δ-Cadinene (3.13 %), 1-Octen-3-ol (2.35 %) and Benzaldehyde (2.31 %). The antioxidant activity of the oils was assessed by measurement of metal chelating activity, the reductive potential, the free radical scavenging (DPPH) assay. The antioxidant activity was compared with that of synthetic antioxidants: butylated hydroxyanisole (BHT) , and the essential oils . The results showed as the Essential oil of M vulgare was evaluated for its antibacterial activities against Gram-positive and Gram negative pathogenic bacteria: Listeria monocytogene, Pseudomonas aeruginosa , Agrobacterium tumefaciens and Salmonella enterica.

Development of Biologically Active Phytosynthesized Silver Nanoparticles Using Marrubium vulgare L. Extracts: Applications and Cytotoxicity Studies

“…Literature data propose Marrubium vulgare L. extracts as potent anti-inflammatory [8,9] and antihypertensive [10] agents, as a source of vasorelaxant secondary metabolites [11], or as antidiabetic and antidyslipidemic agents [12][13][14][15]. Based on its rich phenolic secondary metabolites, the horehound extracts can be successfully used as antioxidant agents [16][17][18], with several studies evaluating its potential through in vitro assays such as the DPPH assay [19][20][21]. Other potential applications of horehound extracts or essential oils are based on their antimicrobial effect.…”

Chemo-type of essential oil of Ocimum basilicum L. from DR Congo and relative in vitro antioxidant potential to the polarity of crude extracts

“…Deficiency of such balance is involved in many disorders, including degenerative disorders such as Alzheimer's disease, cancer, atherosclerosis, diabetes mellitus, hypertension, AIDS and aging [2,3]. Consumption of antioxidants has been suggested as one of the ways to shift the balance towards an adequate redox status [4]. Many years ago, synthetic antioxidants were widely used in foods and pharmaceutical industries; however synthetic antioxidants such as butylated hydroxyanisole and butylated hydroxytoluene (BHT) have been restricted because they were suspected to possess carcinogenic effects [4,5].…”

“…Consumption of antioxidants has been suggested as one of the ways to shift the balance towards an adequate redox status [4]. Many years ago, synthetic antioxidants were widely used in foods and pharmaceutical industries; however synthetic antioxidants such as butylated hydroxyanisole and butylated hydroxytoluene (BHT) have been restricted because they were suspected to possess carcinogenic effects [4,5]. Therefore, the search for new natural antioxidant sources grows and is considered to be more suitable to inhibit oxidation in living systems.…”