The antioxidant and antigenotoxic properties of citrus phenolics limonene and naringin

Bacanlı, Merve; Başaran, Ahmet; Başaran, Nurşen

doi:10.1016/j.fct.2015.04.015

Cited by 149 publications

(66 citation statements)

References 55 publications

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“…At concentrations of 5-2000 lM, naringin showed antioxidant activity and reduced the frequency of DNA damage by H 2 O 2 in Chinese hamster fibroblast (V79) cells (Bacanli et al 2015). In L6 myoblast cells subjected to oxidative stress, pretreatment with naringin (3 or 24 h) reversed the decrease in glutathione (GSH) and increases in both intracellular free radicals and glucose uptake.…”

Section: Effects On Oxidative Stressmentioning

confidence: 99%

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Therapeutic potential of naringin: an overview

Chen

Wang

et al. 2016

Pharmaceutical Biology

313

166

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Context: Naringin is a natural flavanone glycoside that is found in the Chinese herbal medicines and citrus fruits. Studies have demonstrated that naringin possesses numerous biological and pharmacological properties, but few reviews of these studies have been performed. Objective: The present review gathers the fragmented information available in the literature describing the extraction of naringin, its pharmacology and its controlled release formulations. Current research progress and the therapeutic potential of naringin are also discussed. Methods: A literature survey for relevant information regarding the biological and pharmacological properties of naringin was conducted using Pubmed, Sciencedirect, MEDLINE, Springerlink and Google Scholar electronic databases from the year 2007-2015. Results: Naringin modulates signalling pathways and interacts with signalling molecules and thus has a wide range of pharmacological activities, including anti-inflammatory, anti-cancer activities, as well as effects on bone regeneration, metabolic syndrome, oxidative stress, genetic damage and central nervous system (CNS) diseases. Information was gathered that showed the extraction of naringin can be improved using several modifications. There has been some progress in the development of controlled release formulations of naringin. Conclusion: Naringin is a promising candidate for further in vivo studies and clinical use. More detailed studies regarding its mechanism of action are required. ARTICLE HISTORY

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Section: Effects On Oxidative Stressmentioning

confidence: 99%

“…Naringin may avoid H 2 O 2 -induced oxidative damage not only by decreasing DNA damage but also by increasing the DNA repair capacity (Bacanli et al 2015).…”

Section: Effects On Genetic Damagementioning

confidence: 99%

Therapeutic potential of naringin: an overview

Chen

Wang

et al. 2016

Pharmaceutical Biology

313

166

View full text Add to dashboard Cite

show abstract

“…[54,81,100] A variety of phenolic compounds isolated from cinnamon are listed in Table 2. According to Brewer, [101] vanillic acid, caffeic acid, gallic acid, p-coumaric acid, p-hydroxybenzoic acid, and p-hydroxybenzaldehyde are typical polyphenol constituents in cinnamon.…”

Section: Antioxidant Activitymentioning

confidence: 99%

Cinnamon and its derivatives as potential ingredient in functional food—A review

Muhammad

Dewettinck

2017

International Journal of Food Properties

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Cinnamon has been reported to have significant benefits for human health, particularly as an anti-inflammatory, antitumor, anticancer, antidiabetic, and anti-hypertriglyceridemia agent, mainly due to its phytochemical constituents such as phenolic and volatile compounds. The phytochemicals in cinnamon can be extracted from different parts of plant by distillation and by solvent extraction. The use of cinnamon in food and its ability to prevent oxidation and inhibit microbial growth are covered in this review. Its bioaccessibility, safety, and consumer acceptance are comprehensively discussed. This review also clearly shows a route to the use of cinnamon as an ingredient in functional foods. ARTICLE HISTORY

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“…This may be due to its higher composition of 68%-98% of limonene [20]. Limonene is the most popular phenolic compound found in citrus essential oils and has been recognized for its antimicrobial activity [24,25]. Therefore, high composition of limonene leads to high antimicrobial activity.…”

Section: Determination Of Type and Concentration Of Citrus Essential Oilmentioning

confidence: 99%

Enhancement and Preservation of Fresh Orange Juice Using Citrus Essential Oils

Eveline¹,

Puteri²,

Yakhin³

et al. 2017

JAST-B

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Nowadays, consumers are demanding for minimally processed, additive-free, high quality, fresh-like and microbiologically safe foods. However, as food deterioration is the constant threat along the entire food chain, food preservation remains as necessary today as in the past. In this paper, several citrus essential oils, including sweet orange, lemon and lime essential oil applied directly in fresh orange juice as a natural preservative, were analyzed for their antimicrobial activity. The antimicrobial activity of each citrus essential oil was assessed against Saccharomyces cerevisiae, Lactobacillus plantarum and Aspergillus niger using broth macrodilution. Among all citrus essential oils tested, sweet orange essential oil with 0.10% concentration showed significant antimicrobial activity against microorganisms tested. Hence, it was chosen to be applied in the fresh orange juice. Then, shelf life analysis was conducted during 7 d of storage at 5 °C and during 2 d of storage at 25 °C using selected concentration of the selected citrus essential oil in the fresh orange juice. Based on the results obtained, the addition of sweet orange essential oil with 0.10% concentration was not able to prolong the shelf life of the fresh orange juice according to the Indonesian National Standard (SNI). However, the formulation of fresh orange juice itself was able to improve its shelf life when compared to the shelf life of the commercial orange juice.

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The antioxidant and antigenotoxic properties of citrus phenolics limonene and naringin

Cited by 149 publications

References 55 publications

Therapeutic potential of naringin: an overview

Therapeutic potential of naringin: an overview

Cinnamon and its derivatives as potential ingredient in functional food—A review

Enhancement and Preservation of Fresh Orange Juice Using Citrus Essential Oils

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