The Antioxidation Effect of Brown Algae Extract

Shin, Sook Hee; Kang, Sang Mo

doi:10.52660/jksc.2021.27.4.851

J Korean Soc Cosmetol

2021

DOI: 10.52660/jksc.2021.27.4.851

|View full text |Cite

The Antioxidation Effect of Brown Algae Extract

Sook Hee Shin¹,

Sang Mo Kang²

Abstract: This study attempted to investigate the functionality of Dactylosiphon bullosus, Sporochnus radiciformis, and Zonaria diesingiana extracts among algae as cosmetic ingredients. For this, antioxidant experiments were performed. D. bullosus, S. radiciformis and Z. diesingiana extracts were prepared with a 70% ethanol concentration to measure antioxidant activities. In terms of DPPH radical scavenging activity, Z. diesingiana was the highest with 94.20±0.28%. In ABTS radical scavenging activity, Z. diesingiana was… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2021

2024

Publication Types

Select...

Article4

Relationship

Self Cite0

Independent4

Authors

Journals

Cited by 4 publications

References 23 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

A Study on the Antioxidative and Anti-inflammatory Properties of Gloiopeltis furcata Extract Obtained Using Different Concentrations of Ethanol

Kim¹,

Lee²

2023

Asian J Beauty Cosmetol

View full text Add to dashboard Cite

Purpose: This study aimed to explore the differences in the antioxidant activity and anti-inflammatory effects of Gloiopeltis furcata based on its extraction conditions.Methods: 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid (ABTS) assays were performed to determine the antioxidant activity of Gloiopeltis furcata extracts obtained using different concentrations of ethanol. Concomitantly, the concentrations of polyphenols and flavonoids, which are antioxidants present in Gloiopeltis furcata extract, were measured. Additionally, in cell-based experiments, the cytotoxicity and anti-inflammatory activity of a water extract, which exhibited the most potent antioxidative activity among all extracts, was measured.Results: In the DPPH assay, the Gloiopeltis furcata extract exhibited an antioxidant activity of 3.576 mg of ascorbic acid/g, whereas in the ABTS assay, the antioxidant activity was 4.892 mg of ascorbic acid/g. The polyphenol concentration was found to be 35.52±2.32 mg/g, whereas the flavonoid concentration was 0.88±0.34 mg/g. Furthermore, the extract had a cytotoxicity of ≤20% at all concentrations used in the experiment, thus indicating the absence of cytotoxicity and confirming that the extract was effective in reducing inflammation proportionally to its concentration. Moreover, the extract exhibited an anti-inflammatory activity of 47.66%±1.53% at a concentration of 100 μg/mL.Conclusion: Gloiopeltis furcata exhibited the most potent antioxidant activity in its water extract, and it was confirmed that the extract of Gloiopeltis furcata that was obtained through water had low cytotoxicity, an anti-inflammatory effect, and a commercial value.

show abstract

A Study on the Antioxidative and Anti-inflammatory Properties of Gloiopeltis furcata Extract Obtained Using Different Concentrations of Ethanol

Kim¹,

Lee²

2023

Asian J Beauty Cosmetol

View full text Add to dashboard Cite

show abstract

Anti-inflammatory and antioxidant activities of Sargassum horneri extract in RAW264.7 macrophages

Kim¹,

Jo²,

Ramakrishna³

et al. 2021

Phys Act Nutr

View full text Add to dashboard Cite

[Purpose] In this study, we investigated whether a 70% ethanolic (EtOH) extract of Sargassum horneri had antioxidant and anti-inflammatory effects in lipopolysaccharide (LPS)-stimulated macrophage-like RAW 264.7 cells.[Methods] The proximate composition, fatty acids, amino acids, and dietary fiber of S. horneri, various biologically active compounds, and antioxidant activity were analyzed.[Results] The DPPH and ABTS free radical scavenging activities, as well as the reduction power, of the S. horneri extract used here were significantly increased in a concentration-dependent manner. This indicates that S. horneri contains bioactive compounds, such as phenols and flavonoids, that have excellent antioxidant activity. The cellular viability and metabolic activity results confirmed that the extract had no discernible toxicity at concentrations up to 100 μg/mL. The levels of nitrites and cytokines (PGE2, TNF-α and IL-6), which mediate pro-inflammatory effect, were significantly inhibited by treatment with either 50 or 100 μg/mL S. horneri extract, whereas that of IL-1β was significantly inhibited by treatment with 100 μg/mL of the extract. Similarly, the expression of iNOS and COX-2 proteins also decreased according to 50 or 100 μg/mL extract concentrations. NF-κB binding to DNA was also significantly inhibited by treatment with 100 μg/mL of extract.[Conclusion] These results suggest that 70% EtOH extracts of S. horneri can relieve inflammation caused by disease or high intensity exercise.

show abstract

Effects of Gloiopeltis furcata Extract on Antioxidant Activity and Osteoblast Differentiation

Kang

Jung

Park

et al. 2023

JKFN

View full text Add to dashboard Cite

Osteoporosis is a disease characterized by decreased bone strength, decreased bone mass, and bone deterioration. The current study investigates the effects of Gloiopeltis furcata ethanol extract (GFE) on antioxidant activity and osteoblast differentiation in MC3T3-E1 osteoblastic cells. Antioxidant activities of GFE were examined by evaluating 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity, superoxide dismutase (SOD) activity, and total polyphenol content. Results showed that GFE contains 3.04 mg gallic acid equivalents/mL. GFE exhibited significantly strong scavenging activity in the DPPH assay, and 54.26% SOD activity was exhibited at 1,000 mg/mL concentration. Furthermore, GFE significantly increased the viability and proliferation of the MC3T3-E1 osteoblastic cells. Exposure to GFE promoted alkaline phosphatase (ALP) activity and mineralized nodules in MC3T3-E1 cells. Moreover, a dose-dependent increase in the expression of proteins associated with osteoblast growth and differentiation, such as Runx2, ALP, and osterix, was observed in the GFE-treated cells. Taken together, these results indicate that GFE encompasses both antioxidant potential and osteoblast differentiation properties. Thus, we conclude that GFE can potentially be applied as an alternate therapy for the prevention and treatment of osteoporosis.

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

The Antioxidation Effect of Brown Algae Extract

Cited by 4 publications

References 23 publications

A Study on the Antioxidative and Anti-inflammatory Properties of Gloiopeltis furcata Extract Obtained Using Different Concentrations of Ethanol

A Study on the Antioxidative and Anti-inflammatory Properties of Gloiopeltis furcata Extract Obtained Using Different Concentrations of Ethanol

Anti-inflammatory and antioxidant activities of Sargassum horneri extract in RAW264.7 macrophages

Effects of Gloiopeltis furcata Extract on Antioxidant Activity and Osteoblast Differentiation

Contact Info

Product

Resources

About