The antioxidative effects of bioactive products from Sargassum polycystum C. Agardh and Sargassum duplicatum J. Agardh against inflammation and other pathological issues

Effect of solvents on bioactive compounds and antioxidant activity of Padina tetrastromatica and Gracilaria tenuistipitata seaweeds collected from Bangladesh

“…Though, other researcher observed a negative correlation between TPC and antioxidant activity (activity of lipid peroxidation inhibition) in the case of red seaweed which test was not performed in our current research 56 . Furthermore, total phenolics and flavonoid content of various seaweed extracts had a similar positive correlation which is in agreement with the results of other researchers 28 , 57 . Our present finding evidently recommends the existence of phenolic or flavonoid compounds in methanolic extracts may be primarily responsible for the result of the highest antioxidant activity in the crude extracts.…”

Effects of different extraction methods on contents, profiles, and antioxidant abilities of free and bound phenolics of Sargassum polycystum from the South China Sea

“…Furthermore, the free phenolic fraction obtained from 50% acetone had the highest ORAC value, followed sequentially by 50% ethanol, 70% acetone, and 70% ethanol (p < 0.05). Johnson et al (2019) found that acetone extract had (2005) found protective effects of alcoholic extract from S. polycystum on endogenous antioxidant (reduced glutathione) and antioxidant enzymes of liver mitochondria in rats with acetaminophen-induced toxic hepatitis. These results indicated that the free phenolic fraction of S. polycystum exerted potent antioxidant ability and acetoneaqueous mixture afforded the highest antioxidant ability, followed by ethanol-aqueous mixture.…”

“…Sargassum polycystum , a tropical, edible, brown seaweed distributed primarily in Hainan, Guangdong, and Guangxi provinces of China, Malaysia, and Japan has been reported to have health‐promoting effects in traditional Chinese medicine and is locally used as food and medicine (Laboratory of Marine Biology of Institute of South China Sea Oceanography of Chinese Academy of Sciences, 1978 ; Matanjun et al., 2009 ). Recent studies have reported that S. polycystum contains a wide range of bioactive compounds that exert a broad spectrum of biological activities, including anti‐inflammatory, antioxidant, anticancer, antihyperglycemia, and hepatoprotective activities (Chan et al., 2011 ; Johnson et al., 2019 ; Raghavendran et al., 2005 ). Recent research has mainly focused on sulfated polysaccharides and partly on the bioactivity of phenolic‐enriched extracts, which have not been chemically characterized (Palanisamy et al., 2017 ; Raghavendran et al., 2005 ).…”

Antimacrofouling Assays of Sargassum duplicatum Extract in the Settlement Inhibition of Balanus sp. on Wooden Plank Substrate

“…According to Holmstrӧm and Kjelleberg (1999), bioactive compounds produced by several marine organisms can inhibit the settlement or development of a range of surface colonizing species. This occurred because the bioactive compounds are able to cause disturbance to cell wall formation, which in turn, can lead to death of colonizing species (Johnson et al, 2019). Moreover, quinone in S. duplicatum is destructive to cell membranes, thus causing impediment to initiate growth and attachment on a substrate (Ganesan et al, 2008).…”

“…Moreover, quinone in S. duplicatum is destructive to cell membranes, thus causing impediment to initiate growth and attachment on a substrate (Ganesan et al, 2008). This mechanism makes bioactive compounds able to inhibit the attachment of biofouling (Batubara et al, 2016;Johnson et al, 2019). On this account, the crude extract of S. duplicatum can be used as an antifouling agent containing bioactive compounds that are effective in controlling marine organisms settlement (Ganesan et al, 2008;Silkina et al, 2009).…”