While the nature of research, practice, and training in psychotherapy makes it possible for them to be synergistic in advancing best practice and continuous improvement in the field, this potential is just beginning to be mined. In this process, the systematic case study has important roles to play since it captures and analyzes the contextually complex, qualitative and quantitative data that constitute the basic phenomena of the field. This article briefly reviews the dynamics of the research-practice-training synergy and illustrates how they are embodied in the work of Dr. Mikael Thastum at The Anxiety Disorder Clinic for Children and Adolescents (TADCCA) of Aarhus University. As a second example of this synergy and as a comparison to Thastum's Clinic, the parallel work of Brian Chu at the Youth and Depression Clinic (YAD-C) at Rutgers University is reviewed.Key words: synergy in psychotherapy; psychotherapy research; psychotherapy practice; psychotherapy training; cognitive behavior therapy (CBT); youth CBT; case studies; clinical case studies ____________________________________________________________________________ It would seem self-evident that there should be synergy among psychotherapy research, practice, and training. Research helps to identify and document "best practice" principles and procedures; practice is most effective when it incorporates these; and training is most effective when the didactics taught to trainees and their clinical practicum experiences are based on the best practices identified with research.In this context, the systematic case study has important roles to play. First, it's important to note that psychotherapy practice always takes place within the contextual complexities of the individual case. Thus, identifying and richly documenting-both qualitatively and quantitatively-best practice cases is important from a research point of view in identifying the mechanisms and pragmatics leading to good versus poor outcomes in naturalistic, real-world settings. Second, the creation of systematic case studies of best practice can provide guidelines for how practitioners should conduct therapy. Third, systematic case studies can provide explicit models in the clinical training of students who are learning to conduct therapy. Fourth, by learning how to design and write systematic case studies on their own and others' work, students