A strategy is developed for preparing wearable electronic skins (e‐skins) to obtain multiple outputs and realize superhigh sensitivity. In this work, e‐skins are fabricated using colloidal photonic crystals, in which a single layer of microgels is used as a deformation component. The special structure of the e‐skins allows dual outputs of optical and electronic signals in response to pressure changes. The single‐layer structure of the microgel film allows the e‐skin a high‐pressure sensitivity (10.1 kPa−1) and low minimum detection pressure (2 Pa), which enables it to monitor cardiovascular risks in a wearable style. For example, pulse beat spectrum is recorded using the e‐skin, and arterial stiffness index is obtained from the pulse beat spectrum. More importantly, the sensor is used in diagnosing a volunteer with an aneurysm by monitoring his apex beat. The detection results are wirelessly sent to a smartphone by Bluetooth and are displayed through home‐made software. This makes it very convenient to use at home or in the office.