The apoB/apoA-I Ratio is a Strong Predictor of Cardiovascular Risk

Comparison of Lipid and Apolipoprotein Profiles Following Two Exercise Protocols in Overweight Females

“…The result of our study was consistent with that of koozehchian et al (2014), which showed favorable alterations in BMI and body fat percentage levels following specified periods of exercise training (4). Most researchers and guidelines have also reported that BMI and body fat percentage are often associated with CVDs and reduction in their levels may improve lipoprotein profiles (25,26). For instance, Holme et al (19) and Ben Ounis et al (12) exhibited the same findings.…”

The apolipoprotein B/apolipoprotein A-I ratio in healthy men with normolipidemia: limits of variation and relationship with other lipid parameters

“…High concentrations of total cholesterol (TC) and low-density lipoprotein cholesterol (LDL-C) and low concentrations of high-density lipoprotein cholesterol (HDL-C) are recognized as classic lipid risk factors for developing atherosclerotic cardiovascular disease [1]. However, using the conventional lipid indices can result in errors in the assessment of the lipoprotein-related risk of cardiovascular disease [2,3]. A considerable proportion of patients with atherosclerotic disease have TC and LDL-C concentrations within the recommended range, and some patients who achieve significant LDL-C reduction with lipid-lowering therapy still develop cardiovascular disease [4].…”

“…The apoB/apoA-I ratio could discriminate between patients with coronary artery disease (CAD) and those without, even when the CAD patients had normal lipid levels [3]. The cut-off values for the apoB/apoA-I ratio that define a high cardiovascular risk were proposed to be 0.9 for men and 0.8 for women [3,7]. Although the apoB/apoA-I ratio has been evaluated in many studies (mainly in patients with cardiovascular disease), very few studies have reported the variation limits of the apoB/apoA-I ratio in healthy humans and the relationship of this index with other lipid ratios.…”

“…The apoB/apoA-I ratio could discriminate between patients with coronary artery disease (CAD) and those without, even when the CAD patients had normal lipid levels [3]. The cut-off values for the apoB/apoA-I ratio that define a high cardiovascular risk were proposed to be 0.9 for men and 0.8 for women [3,7].…”

“…Multiple clinical and epidemiological studies have shown that the apolipoprotein (apo) B/apoA-I ratio is a superior marker for cardiovascular disease than lipids and lipoproteins or their ratios [2,3,[5][6][7]. The apoB/apoA-I ratio could discriminate between patients with coronary artery disease (CAD) and those without, even when the CAD patients had normal lipid levels [3].…”