The application of a targeted periprostatic nerve block in transperineal template-guided prostate biopsies

Ding, Xuefei; Luan, Yang; Wang, Fei; Xu, Yaozong; Guo, Cheng-Hao; Zhu, Lingyu

doi:10.21037/qims-20-369

Cited by 6 publications

(7 citation statements)

References 29 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The patients felt almost no pain 30 minutes after biopsy. This was similar to the analgesic effect we achieved previously using targeted periprostatic nerve block anaesthesia in targeted biopsy (24). Hence, under the premise of obtaining a good analgesic effect, this method of anesthesia not only shortened the duration of anesthesia and reduced the time of anesthesia operation but also reduced the dose of anesthetic required.…”

Section: Discussionsupporting

confidence: 81%

Application of single-point prostate biopsy in elderly patients with highly suspected prostate cancer

Luan

Xiao²,

Ding³

et al. 2022

Front. Oncol.

View full text Add to dashboard Cite

ObjectiveTo explore the feasibility of single-point prostate biopsy in elderly patients with highly suspected prostate cancer.MethodsForty-three patients with a prostate imaging reporting and data system score (PI-RADS) of 5, age ≥ 80 years and/or PSA ≥ 100 ng/ml and/or Eastern Cooperative Oncology Group score ≥ 2 were enrolled in our hospital from March 2020 to June 2022. Targeted surgery of these patients was performed using only precise local anesthesia in the biopsy area. The biopsy tissues were examined by intraoperative frozen section examination (IFSE). If the result of IFSE was negative, traditional systematic biopsy and further routine pathological examination were performed. The positive rate of biopsy, operation time, complications and pain score were recorded.ResultsThe positive rate of prostate biopsy was 94.7%. The results of IFSE in two patients were negative, and the routine pathological results of further systematic biopsy of those patients were also negative. The visual analog scale and visual numeric scale were 2 (2-4) and 3 (2-3), respectively, during the biopsy procedure. The mean time of operation was 8.5 ± 2.1 min from the beginning of anesthesia to the end of biopsy. It took 35.3 ± 18.7 minutes to obtain the pathological report of IFSE. The incidences of complication hematuria and urinary retention were 10.5% and 2.6%, respectively.ConclusionFor elderly patients with highly suspected prostate cancer, single-point prostate biopsy can be used to quickly and safely obtain pathological results.

show abstract

Section: Discussionsupporting

confidence: 81%

Application of single-point prostate biopsy in elderly patients with highly suspected prostate cancer

Luan

Xiao²,

Ding³

et al. 2022

Front. Oncol.

View full text Add to dashboard Cite

show abstract

“…Guided by MRI, a targeted prostate biopsy can be performed. An mpMRI/TRUS biopsy combines the advantages of the high sensitivity and specificity of the MRI lesion display and the real-time display and flexibility of TRUS, which, to a certain extent, makes up for the deficiency of targeted biopsy guided by MRI in real time (7,11). The equipment does not need to be changed and patients do not need to change position.…”

Section: Discussionmentioning

confidence: 99%

The application of intraoperative frozen section examination in multiparametric magnetic resonance imaging/transrectal ultrasound fusion prostate biopsy during a major pandemic

Ding¹,

Luan²,

Zhu³

et al. 2022

Quant Imaging Med Surg

Self Cite

View full text Add to dashboard Cite

Background: To investigate the value of intraoperative frozen section examination (IFSE) in multiparametric magnetic resonance imaging/transrectal ultrasound (mpMRI/TRUS) fusion prostate biopsy in a major pandemic.Methods: A total of 35 patients were prospectively enrolled in our hospital from March 2020 to January 2021. The mpMRI/TRUS fusion system was used to perform a targeted biopsy, and the collected specimens were examined by IFSE (Observation Group 1). Then, a targeted biopsy was performed again for routine pathological examination (Observation Group 2). Finally, a systemic biopsy was performed, and the obtained specimens were routinely examined (Control Group). The positive rate, single core positive rate, Gleason score, and time to obtain pathological reports were compared between the groups.Results: The positive rate was 48.6% (17/35) in the control group, 48.6% (17/35) in Observation Group 1, and 51.4% (18/35) in Observation Group 2, showing no significant difference (P>0.05). The single core positive rates were 17.8%, 44.6%, and 47.1% in the Control Group, Observation Group 1, and Observation Group 2, respectively. Observation Group 1 and Observation Group 2 were significantly different from the Control Group (P<0.001). No participants in Observation Group 1 had increased or decreased Gleason scores compared with those in Observation Group 2. The time to obtain the pathological report was 0.025±0.014 days and 4.216±1.073 days for Observation Group 1 and Observation Group 2, respectively, showing a significant difference (P<0.001).Conclusions: This study showed that IFSE can not only rapidly obtain the pathological report of an mpMRI/TRUS biopsy, but can also ensure the accuracy of the pathological diagnosis.

show abstract

“…The apex PNB blocks the somatic nerve in the apex of the prostate, one of the most painful areas during biopsy 9 . The apex PNB is usually performed before local transperineal biopsy 10 , 11 . As the location of the target lesion in FBx is different from that in SBx, pain intensity in SBx should be predicted according to the biopsy site, and the optimal local anaesthesia method for FBx should be used.…”

Section: Introductionmentioning

confidence: 99%

Pain control according to the periprostatic nerve block site in magnetic resonance imaging/transrectal targeted prostate biopsy

Yoo

Koo

Chung

et al. 2022

Sci Rep

View full text Add to dashboard Cite

We analyzed the intensity of pain at each site of systemic prostate biopsy (SBx) and compared the intensity of pain among magnetic resonance (MRI)-targeted transrectal biopsies according to the periprostatic nerve block (PNB) site. We collected data from 229 consecutive patients who had undergone MRI-targeted biopsy. Patients were stratified into two groups according to the site of PNB (base versus base and apex PNB). Pain was quantified at the following time points: probe insertion, injection at the prostate base, injection at the prostate apex, MRI cognitive biopsy (CBx), MRI/transrectal ultrasound fusion biopsy (FBx), SBx, and 15 min after biopsy. For all biopsy methods, the average pain were significantly higher in the base PNB group than in the base and apex PNB group (CBx, p < 0.001; FBx, p = 0.015; SBx, p < 0.001). In the base and apex PNB group, FBx was significantly more painful than SBx (p = 0.024). Overall, regardless of the PNB site, pain at the anterior sites was more than that at the posterior sites in FBx (p = 0.039). Base and apex PNB provided better overall pain control than base-only PNB in all biopsy methods. In the base and apex PNB group, FBx was more painful than CBx and SBx.

show abstract

The application of a targeted periprostatic nerve block in transperineal template-guided prostate biopsies

Cited by 6 publications

References 29 publications

Application of single-point prostate biopsy in elderly patients with highly suspected prostate cancer

Application of single-point prostate biopsy in elderly patients with highly suspected prostate cancer

The application of intraoperative frozen section examination in multiparametric magnetic resonance imaging/transrectal ultrasound fusion prostate biopsy during a major pandemic

Pain control according to the periprostatic nerve block site in magnetic resonance imaging/transrectal targeted prostate biopsy

Contact Info

Product

Resources

About