Sedimentation rate, which is the most important parameters of the inland water way performance like Musi River becoming one of a major research topic in Indonesia. The influence of additional pier for the new LRT Bridge constructed parallel to Ampera Bridge to the sedimentation pattern of Musi River was discussed in this paper. Currently, as most of the rivers in Indonesia, a complete field data observation of discharge, sediment characteristic is a luxury one to have. That's why mathematical model, supported by eligible limited field measurements for model calibration and verification, is commonly used to predict the above parameters. Hydrometric survey of water level, sediment samples (both suspended and bed sediment), velocity and bathymetry were conducted to get instantaneous field data. Based on the comparison of two bathymetry map with difference periods of measurements, it was found that the sedimentation rate, was different for high and low tide. Tank model of Sacramento and USLE were used to respectively generate synthetic river discharge and soil surface erosion rate. Hydrodynamic model of SMS 8 was used to predict annual rate of sedimentation. Good comparison of the field measurement and SMS model results was found for current and sediment pattern. The maximum sedimentation occurs during the high tide where the backwater was generated by sea intrusion. The New LRT pier increase the impact of river contractions for both maximum velocity around the Ampera Bridge up to 1.5 time and sedimentation rate behind the pier group of the bridges.