The application of DNA molecular markers in the study of Codonopsis species genetic variation, a review

Fan

Cell Mol Biol (Noisy-le-grand)

et al. 2020

This study aimed to investigate the effect of dexmedetomidine combined with ropivacaine on inflammatory factors in children with axillary brachial plexus block. Ninety patients who underwent upper limb surgery in our hospital from January 2017 to December 2018 were enrolled and divided into groups A and B. Group A (n=40) was treated with ropivacaine as a local anesthetic, and group B (n= 50) was treated with dexmedetomidine combined with ropivacaine as a local anesthetic during surgery. Face, Legs, Activity, Cry, Consolability (FLACC) Behavioral Pain Assessment Scale was employed to evaluate the pain behavior of the children. Intravenous blood (3 ml) was taken before surgery (T0), 30 min (T1) and 3 hours after surgery (T2) respectively to detect serum TNF-α (tumor necrosis factor-α), IL-6 (interleukin-6) and IL-1β (interleukin-1β) levels using ELISA. The adverse reactions in the two groups were observed, and the MAP (mean arterial pressure) and HR (heart rate) were compared before anesthesia, 30 min and 1 hour after block. The FLACC score of both groups showed a marked upward trend (p< 0.001), with that of group B being significantly lower than group A (p< 0.001). Group B presented a remarkably shorter onset time than group A, and the analgesic time was significantly longer (p< 0.001). The incidence of adverse reactions in group B was significantly lower than that in group A (p< 0.05). MAP and HR dropped significantly 30 min and 1 h after block (p< 0.05). MAP and HR were significantly lower in group B than those in group A 30 min and 60 min after block (p< 0.05). As to serum levels of TNF-α, IL-6, and IL-1β, both groups presented notably increased ones after block (p< 0.05). The application of dexmedetomidine combined with ropivacaine in upper limb surgery has a faster onset time and longer duration than ropivacaine alone, which is of certain clinical effect.

Section: Discussionmentioning

confidence: 88%

Application of dexmedetomidine combined with ropivacaine in axillary brachial plexus block in children and its effect on inflammatory factors

Fan

Cell Mol Biol (Noisy-le-grand)

et al. 2020

“…In this study, the Spearman correlation analysis showed the close and positive relationship between these fungi together with bacteria and the environmental factors including AN, AP, TN and TP, UE, CAT and ACP (Figure 8). These factors may be associated with replant problem under CC system (Table 2), which suggests the possible negative effects of microbial diversity on the environmental factors under CC system [39][40][41][42]. Figure 6.…”

Section: 11benefit Of Plants As Results Of Changes In Soil Microbiamentioning

confidence: 99%

Effects of Soil Nutrients, Enzyme Activities and Microbial Composition in Vegetable-Polygonatum Odoratum Rotation Regimes

Chen¹,

Zhang²,

Y³

et al. 2020

Rev. Chim.

The rotation regimes significantly alter soil properties, however, understanding the effect of crop rotation in various crops system was currently limited. The aim of this research was to reveal the variation in crop productivity, soil nutrients, enzyme activities, and bacterial community composition in vegetable-Polygonatum odoratum rotation horticulture. Thus, a 2-year field experiment was carried out under the P.odoratum-P.odoratum rotation (CC) and vegetable-P.odoratum rotation (FC) system through a randomized complete block design comprising of triplicate plots. The results showed that FC promoted most of the beneficial agronomic traits, soil nutrients, enzyme activities, and reducing root rot disease of P.odoratum. High-throughput sequencing revealed a shift in the microbial community groups with high environmental contaminants degradation ability, and a close correlation between increasing microbial diversity and major environmental factors like soil nutrients, enzyme activities under FC cropping system compared with CC. Therefore, crop rotations with vegetable- P.odoratum was recommended in cultivation.

Cell Mol Biol (Noisy-le-grand)

“…This suggests that low-dose insulin combined with electrolyte therapy is related to the alleviation of inflammatory response. Thus inhibiting the levels of inflammatory factors may be one of its therapeutic mechanisms (32)(33)(34)(35)(36)(37)(38)(39)(40)(41)(42)(43)(44)(45)(46)(47)(48)(49)(50)(51).…”

Section: Discussionmentioning

confidence: 99%

Efficacy of low-dose insulin combined with electrolyte in the treatment of pediatric diabetic ketoacidosis and its effect on serum inflammatory factors

Wei

Feng²,

Zhao

2020

Diabetic ketoacidosis (DKA) is a very serious disease that can occur in both types of diabetes (type 1 and 2). It is caused by a combination of high blood sugar and low insulin levels, which can cause the body to produce too much ketone. Ketones are toxic to human organs. This research aimed to investigate the clinical efficacy of low-dose insulin combined with electrolyte in the treatment of pediatric DKA and its effect on serum inflammatory factors. For this purpose, a total of 122 children with DKA admitted to our hospital from April 2013 to May 2016 were selected as research objects. They were divided into group A with 60 cases and group B with 62 cases. Group B was treated with supplemental electrolytes, and group A was treated with low-dose insulin based on group B. The serum levels of TNF-α, IL-6, and IL-18 were measured by enzyme-linked immunosorbent assay (ELISA) before and after treatment, and the blood sugar, sodium, and potassium levels were measured by an automatic biochemical analyzer. The time when blood sugar reached the standard level when acidosis was corrected and hospitalization time was compared between the two groups. The total effective rate of group A was significantly higher than that of group B (p< 0.05). There was no significant difference in blood glucose, sodium, potassium, TNF-α, IL-6, and IL-18 levels between the two groups before treatment. (all p > 0.05). But the blood glucose, sodium and potassium levels in group A were significantly better than those in group B (all p< 0.001). The levels of serum TNF-α, IL-6, and IL-18 in group A were significantly lower than those in group B after treatment (all p< 0.001). After treatment, the time when blood sugar reached the standard level when acidosis was corrected and hospitalization time in group A were significantly shorter than those in group B (all p< 0.001). Low-dose insulin combined with electrolyte supplementation is effective in the treatment of DKA in children, which can effectively control blood sugar, sodium, potassium level, and inflammatory factor concentration.