The application of mineral water in the treatment of chronic obstructive pulmonary disease: a meta-analysis

Lobanov, Andrey; Fesyun, Anatoliy D.; Voronenko, A.G.; Andronov, Sergey; Yakovlev, Maxim Yu.; Rachin, Аndrey P.; Solimene, Umberto; Nikitina, Anfisa M.; Zaitsev, A.R.; KOCHETKOVA, Vasilisa А.; Barashkov, Gleb N.; Mitroshkina, E. E.; Zharkov, A.I.; Кончугова, Т В; Grishechkina, Irina A.; YING, Luo; Bogdanova, Elena; EREMUSHKIN, Michail A.; SAGANOVA, Tatiana R.; REVERCHUK, Igor V.; ZUEV, Andrey V.

doi:10.23736/s2784-8477.21.01915-5

Cited by 2 publications

(2 citation statements)

References 55 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Certainly, this represents the main intrinsic limitation of this systematic review. Furthermore, evidence from a previous meta-analysis is currently available [9], but the effect estimate resulted in a quantitative synthesis characterized by low-quality evidence and, thus, conclusions should be interpreted with caution.…”

Section: Discussionmentioning

confidence: 99%

“…Two reviewers (LC and SG) independently checked the relevant studies identified from the literature search. Citations of previous published relevant reviews and meta-analyses were examined to identify further pertinent studies, if any [5,9,10]. Literature search results were uploaded to Eppi-Reviewer 4 (EPPI-Centre Software.…”

Section: Search Strategy and Study Eligibilitymentioning

confidence: 99%

See 1 more Smart Citation

The Impact of Thermal Water in Asthma and COPD: A Systematic Review According to the PRISMA Statement

Calzetta,

Di Daniele,

Chetta

et al. 2024

JCM

View full text Add to dashboard Cite

Background: Asthma and chronic obstructive pulmonary disease (COPD) are global health challenges leading to substantial morbidity and mortality. While existing guidelines emphasize evidence-based treatments, the potential therapeutic role of thermal water (TW) inhalation remains under-investigated. Methods: This systematic review followed PRISMA-P guidelines and sought to evaluate the impact of TW in asthma and COPD. A thorough literature search, performed up to May 2023, encompassed in vitro, in vivo, randomized controlled trial (RCT), non-RCT, and observational studies. Results: The review included 12 studies reporting different findings. In vitro studies suggested TW could enhance antioxidant capacity and cell proliferation. In a murine model of non-atopic asthma, TW inhalation reduced airway hyperresponsiveness and inflammation. RCTs in COPD patients indicated mixed effects, including improved quality of life, reduced airway oxidant stress, and enhanced exercise tolerance. Asthma patients exposed to water aerosols exhibited improved lung function and reduced airway inflammation. Non-RCTs showed improved lung function and antioxidant activity after TW therapy. Additionally, observational studies reported enhanced lung function and reduced airway inflammation. Conclusion: The current evidence suggests potential benefits of TW therapy in asthma and COPD. However, limited high-quality RCTs and concerns regarding occupational TW exposure necessitate further investigation. While TW therapy offers a non-invasive treatment, its therapeutic potential still needs definitive demonstration. Future research should therefore prioritize well-designed RCTs to thoroughly establish the efficacy and safety of TW as a potential therapeutic intervention for asthma and COPD.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Search Strategy and Study Eligibilitymentioning

confidence: 99%