The application of platelet-rich plasma in the treatment of androgenic alopecia

Vasconcelos, Rossana Cantanhede Farias de; Azuaga, Karla; Arenas, Géssica Cantadori Funes; Vasconcelos, Joao Guilherme Finizola de; Borelli, Natalie Schnaider

doi:10.5935/scd1984-8773.201572658

Cited by 1 publication

(7 citation statements)

References 18 publications

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“…An important point that has been shown by summarizing the review of various studies in this article is that the simultaneous use of platelet rich and minoxidil has reduced the side effects and improved therapeutic performance. So that the simultaneous use of two drugs were compatible with each other and in the follow‐up showed transient and mild side effects 26,29,32 …”

Section: Discussionmentioning

confidence: 96%

“…PRP growth factors act as mediators in cellular maturity and are responsible for restoring damaged tissues. They are angiogenic and elevate local microcirculatory and activate various cellular groups to the benefit of integration and vivaciousness of tissues 32 …”

Section: Discussionmentioning

confidence: 99%

“…They are angiogenic and elevate local microcirculatory and activate various cellular groups to the benefit of integration and vivaciousness of tissues. 32 Fayed et al reported that compared to the placebo group that received saline solution 4.9%, hair growth significantly increased in 31.7% of PRP group patients after 10 sessions (one every 2 weeks).…”

Section: Discussionmentioning

confidence: 99%

“…Minoxidil possesses antibiotic and mitogenic properties. Finasteride on the other hand inhibits 5α‐reductase and therefore reduces dihydrotestosterone levels and extends the anagen phase that leads to an increase of thickness and number of hairs 12‐39 . Dutasteride is another medication used for the treatment of AGA, though it is not approved by the FDA.…”

Section: Introductionmentioning

confidence: 99%

“…Telogen effluvium is a form of non‐scarring non‐inflammatory alopecia, with a rather sudden onset that is not age‐ or gender‐related 13 . Stemoxydine and nioxin are among the drugs used for treating this type of alopecia 14‐37 …”

Section: Introductionmentioning

confidence: 99%

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Systematic review of platelet‐rich plasma in treating alopecia: Focusing on efficacy, safety, and therapeutic durability

Roohaninasab

Goodarzi

Ghassemi

et al. 2021

Dermatologic Therapy

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Considering the different forms, alopecia could be a very common condition with particular therapeutic concerns; thus, recent therapies still require further assessments. Aim of this systematic review was to evaluate efficacy, safety, and therapeutic durability of platelet rich plasma (PRP) in treating various forms of alopecia. A total of 64 articles were found through a systematic search, and eight original articles were included in the study, based on inclusion/exclusion criteria. In most studies (62.5%) patients' conditions had improved by receiving PRP therapy; these cases experienced an increase in growth and thickness of hair. Simultaneous use of PRP and Minoxidil demonstrated the highest rate of improvement and satisfaction. The highest efficacy in patients with alopecia areata was 76% and the lowest efficacy was 31.7% and in patients with androgenetic alopecia the highest efficacy was 42.75% and the lowest reported efficacy was 25.55%. The main side effect was pain due to PRP injection, which disappeared after ending the treatment and only one article reported more serious side effects. Recurrence after treatment was also reported in only one article. PRP is a safe and easy method for treating hair loss and has limited adverse effects. Optimization of this method depends on dosage, number of sessions and their intervals, and injection techniques. According to the results, the use of PRP due to its relatively high efficiency, low and tolerable side effects, and low recurrence rate can be a good method for the treatment of alopecia and hair loss.

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Section: Discussionmentioning

confidence: 96%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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