The application of quaternary ammonium ionic polymers to electroanalysis: Part 2. Voltammetric studies with quaternary ammonium functionalized polymer film‐coated electrodes

Abstract

The application of quaternary ammonium functionalized polymers to voltammetric analysis is described. A glassy carbon electrode coated with a thin film of poly(trihexylviny1ben-zylammonium chloride) exhibited attractive permselectivity to uric acid. Typically, this polymer-modified electrode yielded a linear voltammetric response to uric acid in the concentration range of 1-10 pM. The ion exchange properties of poly(trihexylvinylbenzy1am-monium chloride) was related to the Gibbs-Donnan equation. Also, chronoamperometry was used to probe the charge-transport and response mechanisms within this type of ionic polymer film.

Determination of uric acid in the presence of ascorbic acid with hexacyanoferrate lanthanum film modified electrode

“…So earlier electrochemical procedures based on the oxidation of UA at carbon-based electrodes suffered from the interference from AA that can also be oxidized at close potential value. Therefore, various approaches have been attempted to separate the oxidizing potentials of UA and AA to reduce the interference problem [15][16][17][18][19][20][21][22][23][24][25], such as the adsorption-medium exchange approach [15], enzyme-based techniques [16][17][18][19], the use of polymer-modified electrodes [20,21], the use of electrochemically pretreated carbon paste electrodes [22] and Nafion-coated glassy carbon electrodes [23,24]. Among them, a widely used method is to coat the electrode with an ion-exchange membrane such as polymer-modified electrodes and Nafion film.…”

Determination of Uric Acid at Electrochemically Activated Glassy Carbon Electrode

“…One major problem usually encountered in the determination of uric acid is the interference of ascorbic acid, which is usually present in high concentrations. Various enzyme-based techniques for uric acid determination were promising due to their high selectivity [5][6][7], but these methods were inherently more expensive, and could only achieve a relative high detection limit of about 1 mM. Polymer membrane electrodes, including osmium complex Nafion bilayer [8], over-oxidized polypyrrole film [9], poly(4-vinylpyridine) [10] and polyglycine [11,12], had been developed for the determination of uric acid.…”

Selective Determination of Uric Acid by Using a β-Cyclodextrin Modified Electrode

“…However, a major problem encountered frequently in the detection of UA is the interference of ascorbic acid (H 2 A), which can be oxidized at a potential close to that of UA [4]. Various methods such as the adsorption=medium exchange approach [5], enzyme-based techniques [6][7][8][9], the use of polymer-modified electrodes [10][11][12], the use of electrochemically pretreated carbon paste electrodes [13] or Nafion-coated glassy carbon electrodes [14], have been developed for the selective determination of UA. These voltammetric techniques are more selective, less costly and less time-consuming than those based on colorimetry or spectrophotometry [15].…”