The Application of Stem Cell Sheets for Neuronal Regeneration after Spinal Cord Injury: A Systematic Review of Pre-Clinical Studies

Abstract

Participant or population All animal models with spinal cord injury are included without restriction on animal species and modeling methods. Intervention Stem cell sheets.Comparator Stem cell suspension injection, blank, Gelatin sponge, normal saline, PBS, vehicle, cultural medium. Study designs to be included control studies. Eligibility criteriaThe following criteria were used to determine eligibility for inclusion in this study: (1) use of stem cell sheets; (2) in vivo studies utilizing the SCI animal model; (3) manuscripts written in English. The following types of studies were excluded: (1) manuscript designs including reviews, systematic reviews, meta-analyses, case reports, guidelines, clinical studies, conference INPLASY 1