The application of thermoanalytical methods in the investigation of biological substances

Characterization of Live and Experimentally Degenerated Hyaline Cartilage with Thermal Analysis

“…Thermal analysis of the material requires no preparation procedures. The material could thus be studied without complicated purification procedures which means that the basic molecular structure can be preserved [Bihari-Varga, 1982]. Bihari-Varga concluded that connective tissue, like other tissue, shows considerable changes as the body passes to older age, and that, it is affected by pathological conditions.…”

“…Differential scanning calorimetry (DSC) and thermogravimetric (TG) analysis have been widely used for determining physicochemical transformations that occur during thermal degradation [Bihari-Varga 1982;Collett & Brown, 1998]. These techniques measure net changes in enthalpy and weight as a result of many reactions taking place simultaneously and are particularly useful for indicating the temperature range and the rate of thermal processes as well as giving considerable information on physical and chemical changes [O'Neill, 1964;Richardson, 1997].…”