The application visualization system: a computational environment for scientific visualization

Upson, Craig; Faulhaber, T.A.; Kamins, D.; Laidlaw, David H.; Schlegel, Daniel R.; Vroom, Jeff; Gurwitz, Robert F.; Dam, Andries van

doi:10.1109/38.31462

Cited by 672 publications

(274 citation statements)

References 14 publications

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“…At around the time when scientific visualisation was being established, the concept of visual programming was also becoming prominent [Haeberli 1988;Upson et al 1989]. Conventional programming languages, whether high level or low level, tend to be built around a vocabulary where the 'words' consist of primitives (characters).…”

Section: Visual Programmingmentioning

confidence: 99%

A Visual Workspace for Constructing Hybrid Multidimensional Scaling Algorithms and Coordinating Multiple Views

Ross

Chalmers

2003

Information Visualization

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Data can be distinguished according to volume, variable types and distribution, and each of these characteristics imposes constraints upon the choice of applicable algorithms for their visualisation. This has led to an abundance of often disparate algorithmic techniques. Previous work has shown that a hybrid algorithmic approach can be successful in addressing the impact of data volume on the feasibility of multidimensional scaling (MDS). This paper presents a system and framework in which a user can easily explore algorithms as well as their hybrid conjunctions and the data flowing through them. Visual programming and a novel algorithmic architecture let the user semi-automatically define data flows and the co-ordination of multiple views of algorithmic and visualisation components. We propose that our approach has two main benefits: significant improvements in run times of MDS algorithms can be achieved, and intermediate views of the data and the visualisation program structure can provide greater insight and control over the visualisation process.

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Section: Visual Programmingmentioning

confidence: 99%

A Visual Workspace for Constructing Hybrid Multidimensional Scaling Algorithms and Coordinating Multiple Views

Ross

Chalmers

2003

Information Visualization

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“…CaM's sequence is highly conserved from yeast to man, and is homologous to other key members of this class, including TnC (Nakayama et al, 1992). CaM has been studied extensively by a variety of methods, and is the EF-hand protein with the most complete structural characterization: the threedimensional structure of CaM has been solved in the apo state Zhang et al, 1995) and in the calcium-activated state, both in the absence (Babu et al, 1988;Tayloret al, 1991 ;Chattopadhyaya et al, 1992;Rao et al, 1993) and presence Meador et al, 1992Meador et al, , 1993 (Upson et al, 1989). B: Sequence alignment of CaM N-terminal domain, CaM C-terminal domain, TnC N-terminal domain, TnC C-terminal domain.…”

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confidence: 99%

An interaction‐based analysis of calcium‐induced conformational changes in Ca²⁺ sensor proteins

1998

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Calcium sensor proteins translate transient increases in intracellular calcium levels into metabolic or mechanical responses, by undergoing dramatic conformational changes upon Ca2+ binding. A detailed analysis of the calcium binding-induced conformational changes in the representative calcium sensors calmodulin (CaM) and troponin C was performed to obtain insights into the underlying molecular basis for their response to the binding of calcium. Distance difference matrices, analysis of interresidue contacts, comparisons of interhelical angles, and inspection of structures using molecular graphics were used to make unbiased comparisons of the various structures. The calcium-induced conformational changes in these proteins are dominated by reorganization of the packing of the four helices within each domain. Comparison of the closed and open conformations confirms that calcium binding causes opening within each of the EF-hands. A secondary analysis of the conformation of the C-terminal domain of CaM (Ca"C) clearly shows that Ca"C occupies a closed conformation in the absence of calcium that is distinct from the semi-open conformation observed in the C-terminal EF-hand domains of myosin light chains. These studies provide insight into the structural basis for these changes and into the differential response to calcium binding of various members of the EF-hand calcium-binding protein family. Factors contributing to the stability of the Ca2+-loaded open conformation are discussed, including a new hypothesis that critical hydrophobic interactions stabilize the open conformation in Ca2+ sensors, but are absent in "non-sensor" proteins that remain closed upon Ca2+ binding. A role for methionine residues in stabilizing the open conformation is also proposed.

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“…There exist several dataflow application environments similar to VISSION, such as AVS [22] or Khoros [25]. From an end user point of view, these environments offer the same visual programming, dataflow, and user interface facilities as VISSION.…”

Section: Methodsmentioning

confidence: 99%

A Framework for Generic State Estimation in Computer Vision Applications

Sminchisescu

Telea

2001

Lecture Notes in Computer Science

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Abstract. Experimenting and building integrated, operational systems in computational vision poses both theoretical and practical challenges, involving methodologies from control theory, statistics, optimization, computer graphics, and interaction. Consequently, a control and communication structure is needed to model typical computer vision applications and a flexible architecture is necessary to combine the above mentioned methodologies in an effective implementation. In this paper, we propose a three-layer computer vision framework that offers: a) an application model able to cover a large class of vision applications; b) an architecture that maps this model to modular, flexible and extensible components by means of object-oriented and dataflow mechanisms; and c) a concrete software implementation of the above that allows construction of interactive vision applications. We illustrate how a variety of vision techniques and approaches can be modeled by the proposed framework and we present several complex, application oriented, experimental results.

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The application visualization system: a computational environment for scientific visualization

Cited by 672 publications

References 14 publications

A Visual Workspace for Constructing Hybrid Multidimensional Scaling Algorithms and Coordinating Multiple Views

A Visual Workspace for Constructing Hybrid Multidimensional Scaling Algorithms and Coordinating Multiple Views

An interaction‐based analysis of calcium‐induced conformational changes in Ca²⁺ sensor proteins

A Framework for Generic State Estimation in Computer Vision Applications

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The application visualization system: a computational environment for scientific visualization

Cited by 672 publications

References 14 publications

A Visual Workspace for Constructing Hybrid Multidimensional Scaling Algorithms and Coordinating Multiple Views

A Visual Workspace for Constructing Hybrid Multidimensional Scaling Algorithms and Coordinating Multiple Views

An interaction‐based analysis of calcium‐induced conformational changes in Ca2+ sensor proteins

A Framework for Generic State Estimation in Computer Vision Applications

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Product

Resources

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An interaction‐based analysis of calcium‐induced conformational changes in Ca²⁺ sensor proteins