2015
DOI: 10.1002/jbm.a.35537
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The applications of conductive nanomaterials in the biomedical field

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Cited by 41 publications
(21 citation statements)
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References 117 publications
(310 reference statements)
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“…Since ES could accelerate bone healing, conductive biomaterials that could deliver electrical current locally should be desirable choices for bone regeneration. PLA composites containing conductive polypyrrole or carbon nanotubes (CNTs) both had demonstrated the ability in promoting adhesion, growth and osteogenic differentiation of osteoblasts and MSCs …”
Section: Introductionmentioning
confidence: 99%
“…Since ES could accelerate bone healing, conductive biomaterials that could deliver electrical current locally should be desirable choices for bone regeneration. PLA composites containing conductive polypyrrole or carbon nanotubes (CNTs) both had demonstrated the ability in promoting adhesion, growth and osteogenic differentiation of osteoblasts and MSCs …”
Section: Introductionmentioning
confidence: 99%
“…Since the first use of synthetic biodegradable sutures in the latter half of the 1960s, 1 biodegradable polymers prepared from poly(lactic acid) (PLA), poly(glycolic acid) (PGA), and other degradable poly(a-hydroxy acids) have been widely used in biomedical applications approved by the FDA. Poly (lactide-co-glycolide) acid (PLGA) based on PLA and PGA has been used for fabricating temporary prostheses, 2-5 threedimensional porous scaffolds and films, [6][7][8][9][10][11][12][13][14][15][16][17] controlled/sustained release drug delivery vehicles, [18][19][20][21][22][23][24][25][26] wound closure (surgical sutures and staples), [27][28][29] and implantable thera-peutic devices (orthopedic fixation devices and cardiovascular stents and grafts), [30][31][32][33][34][35][36] all of which have made many significant achievements in tissue engineering, regenerative medicine, gene therapy, controlled drug delivery, and bionanotechnology. 37 PLGA has its hydrolytically labile chemical bonds in its backbone and has been shown to primarily undergo bulk degradation in vivo via chemical hydrolysis of the hydrolytically unstable ester bonds into lactic acid and glycolic acid.…”
Section: Introductionmentioning
confidence: 99%
“…This process leads to generate poly(lactic acid) (PLA) and poly(glycolic acid) (PGA), and the final degradation products are CO 2 and H 2 O which can be excreted from the body by the tricarboxylic acid cycle safely . Regard to its great biocompatibility and good processability, PLGA was approved by the FDA and widely used in biomedical applications such as degradable and absorbable sutures, implants, artificial skin graft and scaffolds, and drug release systems . Especially, as cardiovascular incidents are dramatically increasing, the applications of PLGA in heart patches and polymeric biodegradable stents (BDSs) have been drawn more and more attention.…”
Section: Introductionmentioning
confidence: 99%