Organic residue analysis (ORA) studies residual anthropogenic organic molecules within archaeological matrices, offering valuable insights into various research inquiries. Despite the development of ORA in Latin America, its significance remains largely unrecognised and underrepresented. This paper aims to provide a comprehensive overview of the evolution, status, and prospects of ORA in Latin America. To achieve this, we conducted a thorough bibliographic survey and analysed contributions related to topics such as foodways, psychoactive consumption, the utilisation of paints, dyes, adhesives, binders, activity areas, and residue radiocarbon dating. We examine the geographical distribution of the studies, the flow between countries of sample origin and destination for ORA, and the chronological development in publications. We address challenges encountered in the production of ORA data in Latin America and emphasise the need for multiproxy and multi‐analytical approaches to characterise and identify robust biomarker sets to investigate the use and circulation of local commodities.