The Ascending Testis and the Testis Undescended Since Birth Share the Same Histopathology

Abstract

The ascending testis has the same germ cell count as the primary undescended testis. Yearly followup by the primary care physician is recommended for patients with retractile testes.

Acquired Cryptorchidism: What Should We Know? The Results of a Systematic Review

“…As mentioned above, biopsies taken from ascending testes showed comparable histological findings to biopsies taken from the contra lateral descended testes and primary undescended testes (Rusnack SL et al 2002). Gracia et al (Gracia J et al 1997) reported an impaired spermatogenic potential in 25/ 35 (71.4%) biopsied ascending testes.…”

“…A third hypothesis proposed by Rusnack et al (Rusnack SL et al 2002) who found that primary undescended testes, ascending testes and the contralateral descended testes share the same histopathology concerning the total and differential germ cell counts per tubule. These findings suggest that an endocrine defect could be the cause of acquired UDT, since no thermal effect can be blamed for the decreased germ cell count in the descent testes.…”

Germ cell development in the descended and cryptorchid testis and the effects of hormonal manipulation

“…Men with a history of ascended testis still have subfertility with abnormal spermatogenesis, as subsequent heat-induced defective germ cell maturation in childhood is likely to occur with ascent. On the other hand, Rusnack et al [47] found no difference in histology of ascended testis and primary undescended testis as both groups had equally depressed germ cell numbers. This could be explained by the relatively late age (7 years) of orchidopexy in their group.…”

Common urological problems in children: inguinoscrotal pathologies

“…It has been shown that ascending testis shares a similar histopathology to congenital undescended testis. 31 Orchidopexy is also recommended.…”