The Aspiration of Stomach Contents into The Lungs During Obstetric Anesthesia

Mendelson, Curtis L.

doi:10.1097/00132586-199406000-00059

Cited by 39 publications

(57 citation statements)

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“…Mendelson was the first to describe the pathophysiology of aspiration of gastric contents as a consequence of general anaesthesia in 1946 5. Mendelson described a series of 44 016 obstetric patients undergoing general anaesthesia between 1932 and 1945.…”

Section: Introductionmentioning

confidence: 99%

Pre-procedural fasting in emergency sedation

Thorpe

Benger

2010

Emergency Medicine Journal

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Section: Introductionmentioning

confidence: 99%

Pre-procedural fasting in emergency sedation

Thorpe

Benger

2010

Emergency Medicine Journal

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“…In 1946, prolonged preoperative fasting rules were established, based on Mendelson’s publication concerning the high incidence of pulmonary aspiration in obstetric patients following intraoperative GOR 18. Since then, preventing aspiration after GOR became one of the most important considerations for safe anaesthetic practice in human medicine.…”

Section: Discussionmentioning

confidence: 99%

Rhinitis following intraoperative gastro‐oesophageal reflux in a dog

Flouraki

Kazakos

Savvas

et al. 2019

Vet Record Case Reports

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A four-month-old, male dog underwent surgical repair of femoral and pelvic fracture. The dog was premedicated with acepromazine combined with morphine; anaesthesia was induced with propofol to effect and maintained with isoflurane in 100 per cent oxygen. One hour after induction the dog regurgitated and gastric contents emerged through the nares. At the end of the surgery rhinoscopy and oesophagoscopy were performed. The oesophageal mucosa was apparently normal, while posterior and retrograde rhinoscopy revealed diffused hyperaemia and oedema of the nasal cavity and nasopharyngeal mucosa; food particles and moderate amount of mucous exudates were also seen. Copious lavage was performed, and administration of antibiotics, metoclopramide, cimetidine and sucralfate was initiated. Nasal mucosa was re-evaluated four days later. No abnormalities were detected in both nasal cavities and nasopharynx. The development of rhinitis following regurgitation during anaesthesia should be considered as a possible complication.

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“…During general anaesthesia, patients are at risk of aspirating stomach contents1 and so are usually barred from eating and drinking from the midnight prior to surgery. While stopping food intake is appropriate, limiting clear fluids for so long may be unnecessary as fluids leave the stomach within 2 hours after ingestion 2.…”

Section: General Considerationsmentioning

confidence: 99%

Drugs in the peri-operative period: 1 - stopping or continuing drugs around surgery

1999

DTB

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Many patients admitted to hospital for an operation will be taking medicines which affect, or are affected by, the drugs used during surgery or by the surgical procedure itself. There are few published data on which to base policy in this situation and doctors generally rely on their own experience. In a series of articles, we will review these issues. In this, our first article, we consider how the events surrounding surgery might affect prescribing and give examples of drugs that need to be stopped or continued. Future articles will cover peri-operative drug management in patients: with diabetes mellitus or taking corticosteroids; taking hormone replacement therapy or oral contraceptives; taking drugs for cardiovascular disease.

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The Aspiration of Stomach Contents into The Lungs During Obstetric Anesthesia

Cited by 39 publications

References 0 publications

Pre-procedural fasting in emergency sedation

Pre-procedural fasting in emergency sedation

Rhinitis following intraoperative gastro‐oesophageal reflux in a dog

Drugs in the peri-operative period: 1 - stopping or continuing drugs around surgery

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