The Assessment of Relationship between Fragmented QRS Complex and Left Ventricular Wall Motion Score Index in Patients with ST Elevation Myocardial Infarction Who Underwent Primary Percutaneous Coronary Intervention

Uslu, Nevzat; Gül, Mehmet; Çakmak, Hüseyin Altuğ; Atam, Ali; Püşüroğlu, Hamdi; Satılmışoğlu, Hulusi; Akkaya, Emre; Aksu, Hale Ünal; Kalkan, Ali Kemal; Surgit, Özgür; Ertürk, Mehmet; Aksu, Hüseyin; Eksik, Abdurrahman

doi:10.1111/anec.12180

Cited by 20 publications

(29 citation statements)

References 38 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…This finding is concordant with previous reports which found lower LVEF, and larger left ventricular systolic and diastolic dimensions and volumes in patients with fQRS and CAD. 21,25 As we included only AMI patients, we can assume that appearance of QRS fragmentation even in the early phase of AMI may indicate larger infarct size and worse LV systolic function. This correlation may partially explain the worse prognosis in patients with fQRS (+).…”

Section: Discussionmentioning

confidence: 99%

Prognostic Value of QRS Fragmentation in Patients with Acute Myocardial Infarction: A Meta‐Analysis

Güngör

Özcan²,

Karataş

et al. 2016

Noninvasive Electrocardiol

View full text Add to dashboard Cite

We searched PubMed, Embase, Web of Science, and Cochrane Library up to October 2015 for eligible studies. We selected studies with fQRS defined with 12-lead ECG during the index hospitalization of STEMI/NSTEMI. Primary outcomes were in-hospital and long-term cardiovascular events. In-hospital mortality was significantly higher in fQRS (+) group (99/733; 13.5%) compared to fQRS (-) group (47/1293; 3.6%) (OR 4.03 95% CI 1.81-8.94; P = 0.0006). Long-term mortality rate was higher in fQRS (+) group (89/473; 18.8%) compared to fQRS (-) group (54/1009; 5.3%) (OR 3.93 95% CI 1.92-8.05; P = 0.0002). In addition the frequency of long-term MACE was higher in fQRS (+) group (46.9%) compared to fQRS (-) group (14.6%) (OR 5.13 95% CI 2.77-9.51; P < 0.00001) CONCLUSION: Presence of fQRS on admission ECG was found to be predictor of mortality, MACE, deterioration of LV function, and presence of multivessel disease in patients with STEMI and NSTEMI.

show abstract

Section: Discussionmentioning

confidence: 99%

Prognostic Value of QRS Fragmentation in Patients with Acute Myocardial Infarction: A Meta‐Analysis

Güngör

Özcan²,

Karataş

et al. 2016

Noninvasive Electrocardiol

View full text Add to dashboard Cite

show abstract

“…The fQRS is a simple, inexpensive, and readily available ECG entity that can be easily identified by clinicians. 24) Acute myocardial inflammation and myocardial ischemia may lead to cardiac remodeling that is associated with the fQRS. 25,26) In this study, there was a higher number of fQRS in patients in the deceased group than in the survival group, even though fQRS was not a potential independent biomarker.…”

Section: Discussionmentioning

confidence: 99%

Biomarkers Investigation for In-Hospital Death in Patients With Stanford Type A Acute Aortic Dissection

et al. 2016

View full text Add to dashboard Cite

SummaryThis retrospective study aimed to investigate the predictive value of biomarkers for in-hospital mortality of patients with Stanford type A acute aortic dissection (AAD).AAD is a life-threatening disease with an incidence of about 2.6-3.6 cases per 100,000/year. A total of 67 consecutive Stanford type A AAD patients admitted to hospital were divided into a deceased group and survival group. The baseline information of the patients between two groups was systematically compared, followed by examination of the electrocardiograms (ECG). Based on the follow-up during hospitalization, we investigated the simultaneous assessment of indexes like fragmented QRS complex (fQRS), admission systolic blood pressure (SBP), aortic diameter, surgical management, troponin I (TnI), white blood cell (WBC) count, N-terminal pro-brain natriuretic peptide (NT-proBNP), and D-dimer.The levels of TnI and NT-proBNP, WBC counts, and rate of fQRS (+) in patients of the deceased group were significantly higher than those in the survival group. The male sex (hazard ratio, 10.88; P = 0.001), admission SBP (hazard ratio, 0.98; P = 0.012), NT-proBNP (hazard ratio, 1.00; P = 0.001), and WBC count (hazard ratio, 1.10; P = 0.033) were independently related with in-hospital death. As a single marker, WBC count had the highest sensitivity at 84.6% (specificity 65.9%).Admission SBP, NT-proBNP, and WBC count were potential independent risk factors of in-hospital death in Stanford type A AAD patients. WBC count may be a more accurate predictor of type A AAD than either alone. (Int Heart J 2016; 57: 622-626)

show abstract

“…2 fQRS is an independent predictor of impaired myocardial perfusion, left ventricular dilatation and decreased ejection fraction in patients with ischemic heart disease, and is strongly correlated with adverse outcomes, arrhythmia and mortality in patients with coronary artery disease (CAD). 3-5 …”

Section: Introductionmentioning

confidence: 99%

Fragmented QRS for Risk Stratification in Patients Undergoing First Diagnostic Coronary Angiography

Eyuboglu¹,

Ekinci²,

Karakoyun³

et al. 2016

Arquivos Brasileiros De Cardiologia

View full text Add to dashboard Cite

BackgroundOnly a small proportion of patients referred for coronary angiography with suspected coronary artery disease (CAD) have the diagnosis of obstructive CAD confirmed by the exam. For this reason, further strategies for risk stratification are necessary.ObjectiveTo investigate the relationship of the presence of fragmented QRS (fQRS) on admission electrocardiogram with angiographically detected CAD and CAD severity in patients without known vascular diseases and myocardial fibrosis, undergoing first diagnostic coronary angiography.MethodsWe enrolled 336 consecutive patients undergoing coronary angiography for suspected CAD. The patients were divided into two groups according to the presence or absence of fQRS on admission. We compared the groups regarding the presence and severity of CAD.ResultsSeventy-nine (23.5%) patients had fQRS on admission. There was not a statistically significant difference between patients with fQRS (41.8%) and non-fQRS (30.4%), regarding the presence of CAD (p = 0.059). However, there was a statistically significant difference between patients with fQRS and non-fQRS regarding the presence of stenotic CAD (40.5% vs. 10.5%, p<0.001) and multi vessel disease (25,3% vs. 5.1%, p<0.001). The frequency of fQRS was significantly higher in patients with SYNTAX score >22 compared to patients with SYNTAX score ≤22.ConclusionsOur findings suggest that fQRS may be an indicator of early-stage myocardial damage preceding the appearance of fibrosis and scar, and may be used for risk stratification in patients undergoing first diagnostic coronary angiography

show abstract

The Assessment of Relationship between Fragmented QRS Complex and Left Ventricular Wall Motion Score Index in Patients with ST Elevation Myocardial Infarction Who Underwent Primary Percutaneous Coronary Intervention

Abstract: WMSI was significantly related with the presence of the fQRS, which reflects the linking between impairment of regional left ventricular systolic function and the presence of severe myocardial injury in STEMI.

Cited by 20 publications

References 38 publications

Prognostic Value of QRS Fragmentation in Patients with Acute Myocardial Infarction: A Meta‐Analysis

Prognostic Value of QRS Fragmentation in Patients with Acute Myocardial Infarction: A Meta‐Analysis

Biomarkers Investigation for In-Hospital Death in Patients With Stanford Type A Acute Aortic Dissection

Fragmented QRS for Risk Stratification in Patients Undergoing First Diagnostic Coronary Angiography

Contact Info

Product

Resources

About