The Association Between Alcohol Consumption and Left Ventricular Ejection Fraction

Abstract

The results of previous studies on the relation between alcohol consumption and heart failure (HF) have been inconsistent. This study aimed to evaluate the association between alcohol consumption and left ventricular ejection fraction (LVEF) in a general population.A total of 10,824 adults were examined using a multistage cluster sampling method to select a representative sample of individuals who were at least 35-years old. The participants were asked to provide information about their alcohol consumption. Echocardiograms were obtained, and LVEF was calculated using modified Simpson's rule.Of the 10,824 participants included in the present study, 46.1% were males, and the mean participant age was 54 years; age ranged from 35 to 93 years. The overall prevalence of LVEF< 0.50 and LVEF < 0.40 in the studied population was 11.6% and 2.9%, respectively. The prevalence of LVEF < 0.5 and LVEF < 0.04 was higher in both the moderate and heavy drinker groups than in the nondrinker group (P <0.05). Multivariate logistic regression analyses corrected according to the different levels of alcohol consumption showed that moderate and heavy drinkers had an –1.3-fold and 1.2-fold higher risk of LVEF <0.5, respectively, than nondrinkers (OR: 1.381, 95% CI: 1.115–1.711, P = 0.003 for moderate drinkers; OR: 1.246, 95% CI: 1.064–1.460, P = 0.006 for heavy drinkers). Heavy drinkers had an ∼1.5-fold higher risk of decreased LVEF < 0.4 than nondrinkers (OR: 1.482, 95% CI: 1.117–1.965, P = 0.006). Moderate drinkers did not show a risk of decreased LVEF < 0.4 that was significantly higher than that of nondrinkers (OR: 1.183, 95% CI: 0.774–1.808, P = 0.437).According to these results, we concluded that increased alcohol consumption was associated with decreased LVEF compared with no alcohol consumption in this general population.

Sight-threatening Diabetic Retinopathy and Associated Risk Factors Among Adult Diabetes Patients at Debre Tabor General Hospital, Northwest Ethiopia

“…Alcohol consumption was defined based on National Institute on Alcohol Abuse and Alcoholism: 19 Nondrinkers (ie, abstainers, or no alcohol consumption history), Moderate drinkers (ie, up to one drink/day for women and up to two drinks/day for men), and Heavy drinkers (ie, >1 drink/day for women and >2 drinks/day for men). …”

“…• Moderate physical activity: anyone who performs moderate activity for more than five days for at least 30 min per day or vigorous intensity activity more than three days for at least 20 min per day. 18 Alcohol consumption was defined based on National Institute on Alcohol Abuse and Alcoholism: 19 • Nondrinkers (ie, abstainers, or no alcohol consumption history), • Moderate drinkers (ie, up to one drink/day for women and up to two drinks/day for men), and • Heavy drinkers (ie, >1 drink/day for women and >2 drinks/day for men).…”

The association of ideal cardiovascular health and left ventricle hypertrophy in rural population of northeast China

“…In China, the ethanol weight content differed among the beverages as follows: 5% in beer, 12.5% in red wine, and 45% in hard liquor. [ 17 ] One drink was equivalent to a mean consumption of 15 g ethanol. [ 17 , 18 ] According to the level of alcohol consumption per day, the participants were classified into 3 groups: nondrinkers (abstainers, or no history of alcohol consumption), moderate drinkers (≤1 drink per day for women and ≤2 drinks per day for men), and heavy drinkers (>1 drink per day for women and >2 drinks per day for men).…”

“…[ 17 ] One drink was equivalent to a mean consumption of 15 g ethanol. [ 17 , 18 ] According to the level of alcohol consumption per day, the participants were classified into 3 groups: nondrinkers (abstainers, or no history of alcohol consumption), moderate drinkers (≤1 drink per day for women and ≤2 drinks per day for men), and heavy drinkers (>1 drink per day for women and >2 drinks per day for men). [ 19 ] The definition of alcohol drinking habit was described detailed in our previous study.…”

“…[ 19 ] The definition of alcohol drinking habit was described detailed in our previous study. [ 17 ] In present study, subjects with alcohol drinking habit included moderate drinkers and heavy drinkers.…”