The association between BMI and health-related quality of life in the US population: sex, age and ethnicity matters

Laxy, Michael; Teuner, Christina M.; Holle, Rolf; Kurz, Christoph

doi:10.1038/ijo.2017.252

Cited by 52 publications

(45 citation statements)

References 28 publications

(46 reference statements)

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“…The inverse U-shape relation between the weight status measured by BMI and the quality of life was found in the US population (Laxy et al 2017). A similar pattern was observed in the Norwegian population aged 40-49, with changes in BMI measured by self-reported questionnaire and health-related quality of life measured by SF-36 (Hervik Thorbjørnsen et al 2014).…”

Section: Discussionmentioning

confidence: 58%

“…Studies aimed to assess the nature of relationship between obesity and mortality showed an increased risk of death in higher and lower body mass index (BMI) categories, indicating an inverse U-or J-shape relation. On the other hand, there are some studies indicating that overweight can be neutral or even protective against mortality (Aune et al 2016;Bombak 2014;Orpana et al 2010;Laxy et al 2017;Cohen-Mansfield and Perach 2011).…”

Section: Introductionmentioning

confidence: 99%

“…Research regarding association between BMI and quality of life (QoL) showed an inverse linear trend or inverse U-shaped relation, or when BMI was analyzed as a categorical variable, QoL was impaired among people with overweight or obesity (Laxy et al 2017;Daviglus et al 2003;Jia and Lubetkin 2005;Ul-Haq et al 2013). The results varied depending on the dimension of QoL taken into account or the tools of measurement used.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Changes in Body Mass Index and Quality of Life—Population-Based Follow-up Study COURAGE and COURAGE-POLFUS, Poland

Zawisza

Tobiasz–Adamczyk

Gałaś

et al. 2019

Applied Research Quality Life

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The study aimed to verify an association between changes in body mass index (BMI) and quality of life (QoL) in a 4-year follow-up in a population-based study in Poland. The results covered data from 1557 adults from the general Polish population who participated in the follow-up survey, performed in two waves: 2011 (COURAGE in Europe); 2015/2016 (COURAGE-POLFUS). Anthropometric measurements and a structured questionnaire including the WHOQOL-AGE scale were used. Regression models were applied to verify whether the observed BMI-QoL association is linear or U-shaped. The inverse U-shaped association between BMI changes and QoL among Polish adults was found using a univariable model. This association was observed in women, whereas in men a linear relationship was found. At the population level, weight loss (BMI decrease of 5-10%) was associated with better QoL in healthy people. The reverse was true in sick people, whose weight loss was observed to be an indicator of poorer QoL. In conclusion, the study suggests an inverse U-shaped association between BMI and quality of life. Better QoL may be considered an additional benefit of public weight loss programs for healthy adults. Further studies focusing on people with some chronic diseases are needed.

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Section: Discussionmentioning

confidence: 58%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Changes in Body Mass Index and Quality of Life—Population-Based Follow-up Study COURAGE and COURAGE-POLFUS, Poland

Zawisza

Tobiasz–Adamczyk

Gałaś

et al. 2019

Applied Research Quality Life

View full text Add to dashboard Cite

show abstract

“…Unexpectedly, in contrast to our hypothesis, BMI and education were not signi cantly associated with QoL in black women in univariate models, although those relationships were observed in white women. Previous studies have shown signi cant relationships between BMI, education, and QoL in blacks [9], [10]. However, BMI has shown to be an unreliable parameter for obesity and understanding its relationship on QoL [34].…”

Section: Discussionmentioning

confidence: 99%

“…A recent study has found that middle-aged black women are biologically older (by about 7.5 years) than white women of the same chronological age due to black women's greater exposure to stressors which can negatively impact QoL [8]. Furthermore, in black women, body mass index (BMI) has been shown to have a negative linear relationship with health-related QoL, compared to the inverse-U shape for white women [9]. Black women have consistently higher BMI levels through all levels of education, whereas white women appear to have decreased BMI with increasing education levels.…”

Section: Introductionmentioning

confidence: 99%

Racial Differences in Lifestyle, Demographic, and Health Factors Associated with Quality of Life (QoL) in Midlife Women

Smith

Cardoso-Mendoza

Flaws

et al. 2020

Preprint

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Background Quality of Life (QoL) is a major indicator of an individual’s overall health. Only a few studies have examined the racial differences between QoL, and risk factors associated with health, demographics, and lifestyle in midlife women. Thus, the purpose of our study is to determine racial differences in QoL in menopausal women due to lifestyle, demographic, and health related factors. Methods A stratified ordinal logistic regression model was applied to self-reported questionnaire data from the Midlife Women's Health Study (MWHS) to determine risk factors associated with QoL differences between white and black women during the menopausal transition. Results In multivariate models, our results showed black women who had 3 or 4 comorbidities (moderate) were about 4 times as likely to have higher QoL compared to women who had 0 to 2 comorbidities (95% CI: 1.65,10.78). However, the number of comorbidities was not significantly associated with QoL in white women in univariate or multivariate analysis. Further, BMI, education, and income were not significant factors in QoL in black women but were in white women. Conclusions Overall, our results illustrate that differences in health, demographic, and lifestyle factors are associated with QoL during menopause. Also, we suggest that future studies evaluate stratified models between racial groups to determine race-specific risk factors related to quality of life.

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N‐terminal pro‐brain natriuretic peptide is a prognostic marker for response to intensive chemotherapy, early death, and overall survival in acute myeloid leukemia

et al. 2023

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Patient-related factors are of prognostic importance in acute myeloid leukemia (AML). Likewise, cardiac disorders may limit the tolerance of intensive therapy. Little is known about the prognostic value of N-terminal pro-brain natriuretic peptide (NT-proBNP). We analyzed NT-proBNP levels at diagnosis in 312 AML patients (median age: 61 years; range 17-89 years) treated with 3 + 7-based induction-chemotherapy and consolidation with up to four cycles of intermediate or high-dose ARA-C.NT-proBNP levels were elevated in 199 patients (63.8%), normal (0-125 pg/ml) in 113 (36.2%), and highly elevated (>2000 pg/ml) in 20 patients (6.4%). Median NT-proBNP levels differed significantly among patients with complete remission (153.3 pg/ml), no remission (225.9 pg/ml), or early death (735.5 pg/ml) (p = .002). In multivariate analysis, NT-proBNP, age, and the 2009 European LeukemiaNet (ELN-2009) classification were independent predictors of outcome after induction chemotherapy. Overall survival (OS) differed significantly between patients with normal, moderately elevated, and highly elevated NT-proBNP (p < .001). These differences were observed in all patients and in patients <60 years but not in those ≥60 years. In multivariate analysis, NT-proBNP, age, and ELN-2009 remained independent prognostic variables for OS (p < .01). Together, NT-proBNP is an independent prognostic factor indicating the risk of induction failure, early death, and reduced OS in patients with AML. | INTRODUCTIONAcute myeloid leukemia (AML) is a hematologic malignancy characterized by abnormal proliferation of neoplastic myeloid precursor cells and a maturation defect. 1,2 Despite the availability of curative chemotherapies and hematopoietic stem cell transplantation (HSCT), the prognosis in patients with AML remains poor. Death within the first 60 days after initiation of induction therapy is seen in a substantial

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The association between BMI and health-related quality of life in the US population: sex, age and ethnicity matters

Abstract: The results show that a more differentiated use of BMI cutoffs in scientific discussions and daily practice is indicated. The findings should be considered in the design of future weight loss and weight management programs.

Cited by 52 publications

References 28 publications

Changes in Body Mass Index and Quality of Life—Population-Based Follow-up Study COURAGE and COURAGE-POLFUS, Poland

Changes in Body Mass Index and Quality of Life—Population-Based Follow-up Study COURAGE and COURAGE-POLFUS, Poland

Racial Differences in Lifestyle, Demographic, and Health Factors Associated with Quality of Life (QoL) in Midlife Women

N‐terminal pro‐brain natriuretic peptide is a prognostic marker for response to intensive chemotherapy, early death, and overall survival in acute myeloid leukemia

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