The association between cold exposure and musculoskeletal disorders: a prospective population-based study

Lewis, Charlotte; Stjernbrandt, Albin; Wahlström, Jens

doi:10.1007/s00420-022-01949-2

Cited by 2 publications

(3 citation statements)

References 55 publications

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“…Hence, an urgent imperative lies in conducting further trials that explore the correlation between physical exercise and growing pains. Cold exposure may cause musculoskeletal pain, which has been mentioned in several studies, 11,12,15,26 a finding also supported by the results of this study. However, the mechanism behind cold-induced pain remains insufficiently established, and various explanations were suggested (eg, cold-induced vasospasm, reduced muscular blood flow induces ischemic nociceptive pain, ion channels).…”

Section: Factors Associated With Pain Frequencysupporting

confidence: 91%

An exploration of clinical features and factors associated with pain frequency and pain intensity in children with growing pains: a cross-sectional study from Chongqing, China

Zhang,

Xu,

Leng

et al. 2024

PR9

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Instruction: Growing pains are the most common cause of musculoskeletal pain in children, affecting both children's and caregivers' well-being. The lack of definitive diagnostic criteria complicates diagnosis and treatment. Objectives: This study aims to outline the clinical features and identify factors associated with the frequency and intensity of growing pains in children in Chongqing, China. Methods: A cross-sectional study was conducted in a children's hospital using its Internet hospital follow-up platform. Children initially diagnosed with growing pains between July and September 2022 were enrolled. Sociodemographics, pain locations, duration, frequency, intensity, and potentially related factors were collected. Results: Eight hundred sixty-three children were enrolled (average age: 8.19 ± 3.24 years; 455 boys [52.72%]). Pain frequency was reported as quarterly (62.11%), monthly (24.80%), biweekly (1.74%), weekly (10.08%), and daily (1.27%). The prevalence of mild, moderate, and severe pain was 26.65%, 55.74%, and 17.61%, respectively. The knee was the most common pain location (63.85%), mostly encountered between 4 pm and 5 pm (20.51%). Multivariate analysis revealed that pain frequency negatively correlated with vitamin supplementation during pregnancy, positively correlated with underweight, bad temper, increased exercise, and cold lower extremities. Pain intensity positively correlated with irritability, increased exercise, and pain sensitivity but negatively correlated with age and vitamin supplementation during lactation. Conclusion: Growing pains typically occur on a quarterly basis, predominantly affecting the knees during 4 pm to 5 pm. Factors in sociodemographics, maternal aspect, temperament, and exercise levels can influence pain frequency and intensity. Clinicians should consider these aspects when developing comprehensive strategies for pain management.

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Section: Factors Associated With Pain Frequencysupporting

confidence: 91%

An exploration of clinical features and factors associated with pain frequency and pain intensity in children with growing pains: a cross-sectional study from Chongqing, China

Zhang,

Xu,

Leng

et al. 2024

PR9

View full text Add to dashboard Cite

show abstract

“…During the initial clinical evaluation, demographic information (age, sex, BMI, education level) and clinical information (smoking habits and daily working hours) were collected. For each clinical evaluation, some rating scales were administered by the same physiatrist, such as the Numeric Rating Scale (NRS) [16], to evaluate the extent of the pain; the Oswestry Disability Questionnaire (ODQ) [17], to evaluate the degree of disability caused by low back pain; and the 36-item Short Form Health Survey (SF-36) questionnaire, to assess quality of life [18].…”

Section: Discussionmentioning

confidence: 99%

“…The NRS scale is a quantitative rating scale by which patients are asked to rate their pain on a defined scale, from 0 to 10 [16].…”

Section: Rating Scalesmentioning

confidence: 99%

Combined Rehabilitation with Alpha Lipoic Acid, Acetyl-L-Carnitine, Resveratrol, and Cholecalciferolin Discogenic Sciatica in Young People: A Randomized Clinical Trial

Scaturro,

Vitagliani,

Tomasello

et al. 2023

Medicina

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Background and Objectives: In the Western world, back pain and sciatica are among the main causes of disability and absence from work with significant personal, social, and economic costs. This prospective observational study aims to evaluate the effectiveness of a rehabilitation program combined with the administration of Alpha Lipoic Acid, Acetyl-L-Carnitine, Resveratrol, and Cholecalciferol in the treatment of sciatica due to herniated discs in young patients in terms of pain resolution, postural alterations, taking painkillers, and quality of life. Materials and Methods: A prospective observational study was conducted on 128 patients with sciatica. We divided the sample into 3 groups: the Combo group, which received a combination of rehabilitation protocol and daily therapy with 600 mg Alpha Lipoic Acid, 1000 mg Acetyl-L-Carnitine, 50 mg Resveratrol, and 800 UI Cholecalciferol for 30 days; the Reha group, which received only a rehabilitation protocol; and the Supplement group, which received only oral supplementation with 600 mg Alpha Lipoic Acid, 1000 mg Acetyl-L-Carnitine, 50 mg Resveratrol, and 800 UI Cholecalciferol. Clinical assessments were made at the time of recruitment (T0), 30 days after the start of treatment (T1), and 60 days after the end of treatment (T2). The rating scales were as follows: the Numeric Rating Scale (NRS); the Oswestry Disability Questionnaire (ODQ); and the 36-item Short Form Health Survey (SF-36). All patients also underwent an instrumental stabilometric evaluation. Results: At T1, the Combo group showed statistically superior results compared to the other groups for pain (p < 0.05), disability (p < 0.05), and quality of life (p < 0.05). At T2, the Combo group showed statistically superior results compared to the other groups only for pain (p < 0.05) and quality of life (p < 0.05). From the analysis of the stabilometric evaluation data, we only observed a statistically significant improvement at T2 in the Combo group for the average X (p < 0.05) compared to the other groups. Conclusions: The combined treatment of rehabilitation and supplements with anti-inflammatory, pain-relieving, and antioxidant action is effective in the treatment of sciatica and can be useful in improving postural stability.

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The association between cold exposure and musculoskeletal disorders: a prospective population-based study

Cited by 2 publications

References 55 publications

An exploration of clinical features and factors associated with pain frequency and pain intensity in children with growing pains: a cross-sectional study from Chongqing, China

An exploration of clinical features and factors associated with pain frequency and pain intensity in children with growing pains: a cross-sectional study from Chongqing, China

Combined Rehabilitation with Alpha Lipoic Acid, Acetyl-L-Carnitine, Resveratrol, and Cholecalciferolin Discogenic Sciatica in Young People: A Randomized Clinical Trial

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