The Association between Copper Containing IUCD and Bacterial Vaginosis

Demirezen, Şayeste; Küçük, Ayşegül; Beksaç, Mehmet Sinan

doi:10.21101/cejph.a3339

Cited by 16 publications

(15 citation statements)

References 17 publications

(30 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…(p<0.05) ( Table 1) This correlates with the study by Sayeste Demirezen et al, (10) in which an association between copper IUCD and bacterial vaginosis has been detected. A total of 6 women in whom the Nugents score was 4 to 6 at the time of insertion turned out to be more than 6 during follow up.…”

Section: Resultssupporting

confidence: 90%

Study of Microbial Flora of Female Genital Tract in Intrauterine Contraceptive Device Users

Subha¹,

Selvi²,

Balaji³

et al. 2017

Int.J.Curr.Microbiol.App.Sci

View full text Add to dashboard Cite

Section: Resultssupporting

confidence: 90%

Study of Microbial Flora of Female Genital Tract in Intrauterine Contraceptive Device Users

Subha¹,

Selvi²,

Balaji³

et al. 2017

Int.J.Curr.Microbiol.App.Sci

View full text Add to dashboard Cite

“…Possible explanations for an association between IUD use and BV acquisition include increased anaerobic bacteria in the vagina due to the presence of a string in the vagina or a foreign body in the uterus, or increased volume and duration of menstrual flow in users of the copper IUD. 23,24 We hypothesized that among women initiating contraception, the incidence of BV would be higher among new users of the IUD users compared to new users of COC, ring, and patch.…”

Section: Introductionmentioning

confidence: 99%

Risk of Bacterial Vaginosis in Users of the Intrauterine Device

Madden

Grentzer

Secura

et al. 2012

Sexually Transmitted Diseases

View full text Add to dashboard Cite

BACKGROUND Users of the intrauterine device(IUD) may be at increased risk for bacterial vaginosis (BV). Our objective was to compare the incidence of BV in women using the IUD compared to women using combined oral contraceptives (COC), the contraceptive vaginal ring, and the contraceptive patch. METHODS We prospectively recruited women negative for BV at baseline. Monthly, for six months, participants returned a self-obtained vaginal smear for Gram stain by mail. BV was diagnosed by a Nugent score ≥7. We performed Cox proportional hazards regression to investigate associations between demographic and behavioral characteristics, contraceptive method, and incident BV. RESULTS We enrolled 153 women negative for BV at baseline; 90(59%) women who chose the IUD and 63 (41%) who chose COC, ring, or patch. There were 35 women with BV at one or more time points. The incidence of BV was 37.0% among IUD users and 19.3% in COC, ring, and patch users (p=0.03). In the univariate analysis, race, IUD use, intermediate flora, and irregular vaginal bleeding were significantly associated with BV. In the adjusted model, IUD users were no more likely to acquire BV (HRadj 1.28, 95%CI 0.53–3.06)than COC, ring, and patch users. The associations between intermediate flora and irregular bleeding and BV remained significant (HRadj 3.3095% CI 1.51–7.21, and HRadj 2.54, 95% CI 1.03–6.24 respectively). CONCLUSIONS The association between IUD use and BV may be mediated by irregular vaginal bleeding. Intermediate flora is associated with an increased incidence of BV.

show abstract

“…Earlier studies have found a significant association with the IUCD user bacterial vaginosis cases than controls in populations of the UK; p = 0.04, 27% cf. 14% [33], Indonesia, USA; 47.2% and 29.9% [34], Turkey; p < 0.05 [35]. However, some previous studies showed contradictory results and found no significant difference of IUCD user bacterial vaginosis cases in the populations of India [36], United States [37] and Chile [38].…”

Section: Discussionmentioning

confidence: 96%

Factor Associated to Bacterial Vaginosis in Non-pregnant Women of North Indian Population

Amita¹,

Nain²

2015

J Biotechnol Biomater

View full text Add to dashboard Cite

Bacterial vaginosis is currently the most prevalent cause of vaginal infection and vaginal discharge among the sexually active women. Bacterial vaginosis is a complex microbiological disease. Therefore, we aimed to determine the association of risk factors for bacterial vaginosis patients. In the prospective study, we enrolled a total of 300 nonpregnant women. One hundred and twenty six women were positive for bacterial vaginosis, confirmed by Amsel's criteria and Nugent's scoring. One hundred and seventy four women were unrelated control. Frequency of intrauterine contraceptive device differed significantly between bacterial vaginosis and healthy individuals (29.4% versus 17.2%, p=0.017; OR=1.70). Individuals with a sexual transmitted disease in partners was conferred significantly higher risk for bacterial vaginosis (p=0.001, OR=8.28). However, use of contraception, vaginal douching, and use of condom did not modulate the risk of bacterial vaginosis. Individuals with the use of intrauterine contraceptive device and presence of sexual transmitted disease in partners conferred a higher risk for bacterial vaginosis.

show abstract

The Association between Copper Containing IUCD and Bacterial Vaginosis

Cited by 16 publications

References 17 publications

Study of Microbial Flora of Female Genital Tract in Intrauterine Contraceptive Device Users

Study of Microbial Flora of Female Genital Tract in Intrauterine Contraceptive Device Users

Risk of Bacterial Vaginosis in Users of the Intrauterine Device

Factor Associated to Bacterial Vaginosis in Non-pregnant Women of North Indian Population

Contact Info

Product

Resources

About