The association between dose of hemodialysis and patients mortality in a prospective cohort study

Liu, Shuxin; Wang, Zhihong; Zhang, Shuang; Xiao, Jia; You, Lian-Lian; Dong, Chao; Wang, Xuena; Wang, Zhenzhen; Wang, Shengnan; Song, Jia-Ni; Yan, Xin-Yi; Yu, Shu-Fan; Zhang, Yinan

doi:10.1038/s41598-022-17943-0

Cited by 10 publications

(5 citation statements)

References 45 publications

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“…Besides, worldwide, kidney replacement therapy is more commonly provided to men than women, possibly due to biological factors and the accelerated development of chronic kidney disease in men. The current result was similar to Liu et al, [35] and Lima et al, [36] who noticed that 50% of respondents were males. Pertaining to residence, the current research results proved that approximately three quarters of the participants originated from rural regions.…”

Section: Discussionsupporting

confidence: 91%

Effect of progressive muscle relaxation technique on anxiety and sleep quality among hemodialysis patients

Sanad¹,

Aziz²,

Hassan³

et al. 2023

Int. J. Adv. Psychiatric Nurs.

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Background: Patients on hemodialysis suffer from a variety of stressors and psychological problems as sleep disorders and anxiety. Progressive muscle relaxation is one of nursing modalities that can be applied to patients undergoing hemodialysis to decrease these problems. Aim: Evaluate the effect of progressive muscle relaxation technique on anxiety and sleep quality among hemodialysis patients. Research design:The aim of this study was achieved through utilizing a pre-posttest quasiexperimental research design. Sample: 60 adult patients with chronic renal failure who were receiving hemodialysis at the Minia University Hospital for Urology and Nephrology were chosen as a purposeful sample. Tools: Structured Interview Questionnaire Sheet, Beck Anxiety Inventory and Pittsburg Sleeping Quality Index were utilized in this research. Results: The global mean score of anxiety and sleep quality levels reduced immediately and post implementing the training program. Statistical significant positive correlation was observed between the global sleep quality and anxiety scores at the pre, immediate and post training program. Conclusion: Progressive muscle relaxation technique is an efficient method to mitigate anxiety and enhance quality of sleep for patients receiving hemodialysis. Recommendation: A training program should be applied for nephrology nurses to equip them with adequate knowledge and skills regarding how to integrate progressive muscle relaxation technique in their daily care for relieving the psychological consequences and reliance on pharmacological treatments.

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Section: Discussionsupporting

confidence: 91%

Effect of progressive muscle relaxation technique on anxiety and sleep quality among hemodialysis patients

Sanad¹,

Aziz²,

Hassan³

et al. 2023

Int. J. Adv. Psychiatric Nurs.

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“…Second, as a result of long-term hemodialysis, MHD patients’ physical function, muscle strength, and functional motor ability have declined, their social function has gradually weakened, and they have become more dependent on their caregivers for support and assistance, which has brought double pressure on the patients’ body and psychology, and exacerbated social alienation. Lastly, MHD patients have high rates of cardiovascular events and mortality [ 15 , 71 ], and patients have negative perceptions of the disease [ 72 ], leading to fear of disease progression and increased social alienation.…”

Section: Discussionmentioning

confidence: 99%

Association between illness perception and social alienation among maintenance hemodialysis patients: The mediating role of fear of progression

Zhu,

Wu,

et al. 2024

PLoS ONE

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Purpose This study aimed to investigate the mediating role of fear of progression on illness perception and social alienation among maintenance hemodialysis (MHD) patients. Background MHD is frequently accompanied by increased pain and complications such as itchy skin, chronic fatigue, and muscle spasms. Cardiovascular disease rates are also elevated among MHD patients, which can heighten their anxiety regarding prognosis and treatment discomfort. This chronic fear may severely impact social functioning, leading patients to withdraw from interpersonal interactions and experience heightened helplessness and loneliness. Further investigation is necessary to understand the factors behind the high level of social alienation in MHD patients and their underlying mechanisms. Design A cross-sectional study guided by the STROBE. Methods A convenience sample of 230 MHD patients were enrolled from January to May 2023. Data including demographic and clinical characteristics, illness perception, fear of progression, and social alienation were collected. Descriptive analysis and Pearson correlations were conducted using IBM SPSS version 25.0. The mediating effect was analyzed using Model 4 of the PROCESS macro for SPSS, with the Bootstrap method employed to assess its significance. Results The score of social alienation in MHD patients was high, with illness perception and fear of progression both significantly correlated with social alienation. In the mediating effects model, illness perception can predict social alienation in MHD patients, and fear of progression use plays a part in mediating the process by which illness perception affects social alienation. The Kappa Squared (κ2) value of 21.9%, suggests a medium effect size. Conclusions Illness perception directly predicts social alienation in MHD patients and exerts an indirect effect through the mediating role of fear of progression. Suggests that healthcare professionals should concentrate on MHD patients with high negative illness perceptions to alleviate their fear of progression, thereby decreasing the level of social alienation and enhancing their integration into society.

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“…The NKF-KDOQI guidelines recommend that for patients with low residual natural renal clearance (KRU, 2 mL/min), the target dialysis dose for thrice-weekly HD is 1.2–1.4 spKt/V per dialysis [ 6 ]. It has been shown that spKt/V is a significant predictor of morbidity and mortality in patients receiving HD [ 20 , 21 ]. Studies have shown a strong correlation between Kt/V and mortality in HD patients [ 22 ].…”

Section: Discussionmentioning

confidence: 99%

Single-pool model urea clearance index is associated with sarcopenia and nutritional status in patients undergoing maintenance hemodialysis: a cross-sectional study

Li,

Xing,

et al. 2024

BMC Nephrol

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Background The single-pool model urea clearance index (single-pool Kt/Vurea; spKt/V) is the most commonly used method for dialysis adequacy assessment. However, only a few studies have examined the relationship between spKt/V values and parameters related to sarcopenia and nutritional status. This study aimed to evaluate whether the spKt/V is an indicator of sarcopenia and nutritional status in patients undergoing maintenance hemodialysis (MHD). Methods A total of 142 patients were included in this single-center, cross-sectional study. Venous blood samples were collected shortly before the hemodialysis session. The adequacy of dialysis in patients receiving MHD was assessed using spKt/V. Sarcopenia was identified according to the Asian Working Group for Sarcopenia (2019) definition. Receiver operating characteristic curve and area under the curve were used to evaluate the predictive value of spKt/V in sarcopenia. Univariate and multivariate binary logistic regression analyses were used to determine the association between spKt/V and sarcopenia and nutritional status. Results The mean spKt/V level was 1.3 ± 0.2, the prevalence of sarcopenia was 15.5% in patients on MHD. The best cutoff value of spKt/V in sarcopenia was 1.45 for both sexes, 1.33 and 1.45 for men and women, respectively (P < 0.05). The multivariate binary logistic regression shown that the spKt/V was independently positively associated with sarcopenia (OR = 122.88, 95% CI = 0.64–0.87, P = 0.002). Grouping spKt/V by the best cutoff value, when spKt/V ≥ 1.45, the OR of sarcopenia was 11.75 (95% CI = 3.16–43.67, P < 0.001). Subgroup analyses showed that when spKt/V ≥ 1.33 in men and spKt/V ≥ 1.45 in woman, the OR of sarcopenia was 9.73 (95% CI = 2.25–42.11, P = 0.002) and 14.52 (95% CI = 1.06–199.67, P = 0.045), respectively. Conclusions The present study showed that spKt/V was an important influencing factor of sarcopenia and malnutrition in Asian patients on MHD.

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The association between dose of hemodialysis and patients mortality in a prospective cohort study

Cited by 10 publications

References 45 publications

Effect of progressive muscle relaxation technique on anxiety and sleep quality among hemodialysis patients

Effect of progressive muscle relaxation technique on anxiety and sleep quality among hemodialysis patients

Association between illness perception and social alienation among maintenance hemodialysis patients: The mediating role of fear of progression

Single-pool model urea clearance index is associated with sarcopenia and nutritional status in patients undergoing maintenance hemodialysis: a cross-sectional study

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