The Association between Foveal Floor Measurements and Macular Hole Size

Murphy, Declan C; Melville, Harry; George, Grace; Grinton, Michael; Chen, Yunzi; Rees, Jon; Tyagi, Pallavi; Wickham, Louisa; Steel, David

doi:10.1016/j.oret.2020.09.023

Cited by 6 publications

(5 citation statements)

References 28 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This may relate partly to the person affected being unaware of the problem, and hence presenting late especially if it is their nondominant eye effected for example. It may also relate to anatomical characteristics, including foveal floor and vitreomacular traction width, both of which are known to vary between individuals and differ according to ethnicity 45,46 . The rate by which an iFTMH enlarges also depends on the presenting size; smaller holes growing faster than larger holes 47,48 .…”

Section: Discussionmentioning

confidence: 99%

The Effect of Macular Hole Duration on Surgical Outcomes

Murphy

Al-Zubaidy²,

Lois³

et al. 2023

Ophthalmology

Self Cite

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 99%

The Effect of Macular Hole Duration on Surgical Outcomes

Murphy

Al-Zubaidy²,

Lois³

et al. 2023

Ophthalmology

Self Cite

View full text Add to dashboard Cite

“…Epiretinal proliferations (EP) thickness was specified at the thickest part of the tissue formation above the ILM. Foveal floor thickness was measured at the deepest point of the foveal cavity or foveal pit as proposed by Murphy et al (2021). Loss of neuroretinal tissue included a foveal cavity affecting the outer retinal layers resulting in a thinning of the foveal floor.…”

Section: Methodsmentioning

confidence: 99%

“…2006; Murphy et al. 2021). It allows detailed visualization of macular hole development and differentiation of various morphological subtypes.…”

Section: Introductionmentioning

confidence: 99%

“…With these advancements, we are now able to observe a variety of anatomic abnormalities in the neuroretina in eyes with partial-thickness macular holes that we were previously unable to visualize. To date, OCT imaging proves to be the gold standard in the diagnosis of these eyes (Haouchine et al 2004;Witkin et al 2006;Murphy et al 2021). It allows detailed visualization of macular hole development and differentiation of various morphological subtypes.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Evaluation of neuroretinal integrity in optical coherence tomography‐graded eyes with partial‐thickness macular holes

Stino

Wassermann

Ristl

et al. 2022

Acta Ophthalmologica

View full text Add to dashboard Cite

Purpose: To evaluate neuroretinal integrity in different subtypes of optical coherence tomography (OCT)-graded partial-thickness macular holes. Methods: Fovea-centred SD-OCT images (Cirrus, Carl Zeiss Meditec AG; Spectralis, Heidelberg Engineering GmbH) and visual acuity (VA) acquired at every visit were analysed by two retina specialists retrospectively in 71 eyes of 65 patients. Partial-thickness macular holes were classified as lamellar macular hole (LMH), epiretinal membrane foveoschisis (ERMF) or macular pseudohole (MPH). Results: Lamellar macular hole, ERMF and MPH were diagnosed in 33 (47%), 31 (43%) and 7 (10%) eyes with a VA of 0.18 AE 0.25, 0.15 AE 0.2, and 0.06 AE 0.08 (p = 0.323), respectively. Median follow-up time was 11 (interquartile range 4-32.5), 10 (interquartile range 5-18) and 19 (interquartile range 8-24) months in LMH, ERMF and MPH. In all subgroups, VA remained stable during the follow-up (p = 0.652, p = 0.915 and p = 1.000). Epiretinal proliferations (EP) were present in 12 LMH and 3 ERMF. At baseline, eyes with EP had significantly worse VA (p < 0.001), wider foveal cavities (p = 0.007) and thinner foveal floors (p < 0.001) compared with eyes without EP. Twelve out of 15 eyes with EP showed exudative cystoid spaces. Among all 71 eyes, 51 remained morphologically and functionally stable during follow-up. Conclusion: In our study cohort, EP are associated with worse VA and advanced neuroretinal tissue loss presenting with wider foveal cavities and thinner foveal floors. During the follow-up period, VA remained stable in all entities of partialthickness macular holes.

show abstract

“…Previous studies also determined a variation in the foveal morphology among different ethnic cohorts: the eyes of Black patients presented on OCT a larger, deeper, and broader foveal pits associated with a thinner central foveal neuroretinal thickness compared to White and Asian counterparts [ 3 ]. Murphy et al found that even the size in unilateral macular holes correlated with the foveal floor of the fellow eye [ 4 ].…”

mentioning

confidence: 99%