The association between lumbar spine radiographic features and low back pain: A systematic review and meta-analysis

Raastad, Joachim; Reiman, Michael P.; Coeytaux, Remy R; Ledbetter, Leila; Goode, Adam P.

doi:10.1016/j.semarthrit.2014.10.006

Cited by 94 publications

(79 citation statements)

References 56 publications

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“…Lumbar disc degeneration and its associated changes such as disc space narrowing are related to LBP (24). Lumbar disc degeneration is a common musculoskeletal condition, the prevalence of which increases with age (25)(26)(27)(28)(29).…”

Section: Evidence-based Medicinementioning

confidence: 99%

Increased low back pain prevalence in females than in males after menopause age: evidences based on synthetic literature review

Wáng

Káplár

2016

Quant. Imaging Med. Surg.

212

160

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Female sex hormones play an important role in the etiology and pathophysiology of a variety of musculoskeletal degenerative diseases. Postmenopausal women show accelerated disc degeneration due to relative estrogen deficiency. This literature review aims to validate or falsify this hypothesis, i.e., while overall females have higher prevalence of low back pain (LBP) across all age groups, this male vs. female difference in LBP prevalence further increases after female menopause age. The literature search was performed on PubMed on January 2, 2016. The search word combination was (low back pain) AND prevalence AND [(males OR men) AND (females OR women)].The following criteria were taken to include the papers for synthetic analysis: (I) only English primary literatures on nonspecific pain; (II) only prospective studies on general population, but not population with occupational LBP causes, of both males and female subjects studied using the same LBP criterion, ages-specific information available, and males and female subjects were agematched; (III) studies without major quality flaws. In total 98 studies with 772,927 subjects were analyzed.According to the information in the literature, participant subjects were divided into four age groups: (I) school age children group: 6-19 years; (II) young and middle aged group: 20-50 years; (III) mixed age group: data from studies did not differentiate age groups; (IV) elderly group: ≥50 years old. When individual studies were not weighted by participant number and each individual study is represented as one entry regardless of their sample size, the median LBP prevalence ratio of female vs. males was 1.310, 1.140, 1.220, and 1.270 respectively for the four age groups. When individual studies were weighted by participant number, the LBP prevalence ratio of female vs. males was 1.360, 1.127, 1.185, and 1.280 respectively for the four groups.The higher LBP prevalence in school age girls than in school age boys is likely due to psychological factors, female hormone fluctuation, and menstruation. Compared with young and middle aged subjects, a further increased LBP prevalence in females than in males was noted after menopause age.

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Section: Evidence-based Medicinementioning

confidence: 99%

Increased low back pain prevalence in females than in males after menopause age: evidences based on synthetic literature review

Wáng

Káplár

2016

Quant. Imaging Med. Surg.

212

160

View full text Add to dashboard Cite

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“…In Swedish multicenter prospective observational study of 3009 male participants between 69 and 81 years of age, Ghanei et al [12] reported that the 1-year prevalence of LBP was approximately 50 % in older males. Although degenerative findings are common in imaging studies in the elderly, it is also well known that these degenerative findings are not necessarily associated with LBP [13][14][15][16][17][18][19][20][21][22][23]. Dayo et al [24] reported that the cause of chronic LBP could not be identified by various imaging studies in 85 % of cases, and LBP without any evident cause is commonly referred to as non-specific LBP.…”

Section: Etiologymentioning

confidence: 99%

Spinal Disorders as a Cause of Locomotive Syndrome: The Influence on Functional Mobility and Activities of Daily Living

Makino

Kaito

Yonenobu

2016

Clinic Rev Bone Miner Metab

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Spinal disorders are one of the most common causes of locomotive syndrome because the spine plays an important role as the locomotive organs which provide the three functions: body frames, junction sites, and motors/ regulators. Previous reports have shown that low back pain or leg pain and/or intermittent claudication due to spinal stenosis in lumbar spine disorders, gait abnormality due to degenerative cervical myelopathy in cervical spine disorders, and trunk imbalance due to adult spinal deformity have negative effects on walking speed, walking distance, and movement ability, thereby increasing the risk of falling. Patients for whom conservative managements have failed are considered for surgical treatment. However, degenerative changes on radiographical examinations are sometimes observed in asymptomatic elderly people, which suggests that degenerative changes are not always the cause of pain or disability in the elderly, particularly non-specific low back pain and neck pain. Therefore, the evidence is insufficient regarding how effective surgical treatments can be for improving walking and movement ability and social participation of elderly patients. In addition to better evidence for the efficacy of various treatments, more attention concerning checkups and prevention of locomotive syndrome are urgently needed in aging populations.

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“…Though pain is the most common reason why patients undergo imaging of the spine [4], the evidence in the literature does not support the routine use of radiological imaging to diagnose zygapophysial joint pain [5]- [10]. The identification of a painful joint seems difficult, because the literature does not report any correlation between the clinical symptoms of low back pain and degenerative spinal changes on radiological imaging studies [11], including radiographs, magnetic resonance imaging (MRI), and computed tomography [8] [9]. Specifically, the association between degenerative changes in the lumbar facet joints and symptomatic low back pain remains unclear and is a subject of ongoing debate [5] [6] [7] [8].…”

Section: Introductionmentioning

confidence: 99%

Association between Magnetic Resonance Imaging and the Result of Medial Branch Blocks

Klessinger

Freund

2017

PST

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The aim of this retrospective practice audit was to assess the correlation between painful zygapophysial joints and changes seen in magnetic resonance imaging (MRI). Patients with unilateral pain were tested with controlled medial branch blocks. The MRI scans of patients with a positive response were compared blinded with normal MRI scans. The dimensions of the joint were assessed and osteoarthritis was graded. Fifteen symptomatic patients and 15 asymptomatic patients were included and evaluated. Comparison of the joints showed that the maximum diameter of symptomatic joints was significantly larger, and the grading of osteoarthritis was significantly higher for symptomatic joints. No healthy patient was assigned a grade 3. Grades 2 and 3 were found significantly more often in symptomatic patients. Only one symptomatic joint was assigned grade 0. Grade 0 was found significantly more often in asymptomatic patients. The presented MRI technique has limited value as a diagnostic test for lumbar zygapophysial joint pain. It is not possible to detect a single symptomatic joint. However, the osteoarthritis grading for the lumbar zygapophysial joints might be helpful for finding predictors for negative response if the results of the rating are grade zero. Therefore, unnecessary medial branch blocks might be avoided.

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The association between lumbar spine radiographic features and low back pain: A systematic review and meta-analysis

Cited by 94 publications

References 56 publications

Increased low back pain prevalence in females than in males after menopause age: evidences based on synthetic literature review

Increased low back pain prevalence in females than in males after menopause age: evidences based on synthetic literature review

Spinal Disorders as a Cause of Locomotive Syndrome: The Influence on Functional Mobility and Activities of Daily Living

Association between Magnetic Resonance Imaging and the Result of Medial Branch Blocks

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