The association between metabolic profile indices, clinical parameters, and ultrasound measurement of backfat thickness during the periparturient period of dairy cows

Cellini, M.; Hussein, Hussein Awad; Elsayed, Hanan K.; Sayed, Arafat S.

doi:10.1007/s00580-019-02923-0

Cited by 5 publications

(8 citation statements)

References 40 publications

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“…Measurement of specific serum metabolites allows the evaluation of adequacy of the main metabolic pathways associated with energy, protein, and minerals and then provides useful information related to nutrition and animal health to optimize the productive and reproductive potential of dairy herds [1]. Recently, using of blood metabolic profiling has acquired relevance for the study and diagnosis of various metabolic and reproductive disorders [2]. Blood parameters including glucose, non-esterified fatty acids (NEFA), β-hydroxybutyric acid (BHBA), cholesterol, and enzymes and proteins had been reviewed recently to be of great interest for metabolic profiling of dairy herds [3].…”

Section: Introductionmentioning

confidence: 99%

24-h variations of blood serum metabolites in high yielding dairy cows and calves

2020

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Background Blood profile testing is commonly used to monitor herd health status, diagnose disorders, and predict the risk of diseases in cows and calves, with subsequent optimization the production of dairy herds. By understanding the physiological ranges of serum metabolites relative to age, lactation stage, and the sampling time in healthy cows and calves, the dairy practitioners can accurately diagnose abnormalities with a blood test. The effect of sampling time on the variation of serum metabolites within 24 h were evaluated in 83 cattle. All animals were originated from a dairy herd, where the animals, based on their ages and lactation stages, were classified into eight groups. The blood samples were collected from each animal every 4 h within a day. Results The time of sampling within the day showed significant influences on the serum concentrations of glucose, β-hydroxybutyric acid (BHBA) and urea. BHBA was the most metabolite that showed day variation among cows’ groups. Furthermore, the concentrations of total cholesterol were the most stable metabolite in all groups. The mean values of albumin, total proteins, glucose, non-esterified fatty acids (NEFA), BHBA, total cholesterol, total bilirubin, urea, and creatinine revealed significant variations among the different studied groups. Conclusions A certain suitable time of blood sample collection cannot be recommended. However, care shall be taken for the time of sampling for measurements of glucose, NEFA, BHBA and urea, otherwise the comparative values of these metabolites at different sampling time points may differ significantly from each other’s, without a disease cause. It may be recommended, for metabolic assessment of dairy herds, classification the subjects into different groups based on lactation stages and ages of animals.

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Section: Introductionmentioning

confidence: 99%

24-h variations of blood serum metabolites in high yielding dairy cows and calves

2020

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“…In this study, the serum levels of NEFA were higher in single-and multiple-bearing ewes at 1-week pre-lambing, indicating that animals come in a period of negative energy balance during this time. As mentioned elsewhere (Cellini et al, 2019), dairy animals responded to their negative energy balance by mobilizing large amounts of body fat, leading to increased blood concentrations of NEFA. Moreover, in this research on the prepartum transition, NEFA levels were higher in ewes with multiple lambs than those with single lambs, indicating that the degree of fat mobilization is higher in multiple-bearing ewes than in single-bearing ones.…”

Section: Ta B L Ementioning

confidence: 82%

Variations of blood metabolites in single‐ and multiple‐bearing Ossimi ewes during the transition period

Hussein,

Mohammed Omer,

Karam

2024

Reprod Domestic Animals

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Evaluation of the metabolic profile indices allows early detection and treatment of various metabolic disorders during the transition period in ewes. This study aimed to determine the variations in the blood metabolites around lambing in Ossimi ewes. The blood metabolites were investigated in ewes with single (n = 27) and multiple (n = 9) lambs at 3‐ and 1‐week pre‐lambing and 3‐week post‐lambing. The plasma concentrations of glucose were higher in single‐bearing ewes than those in multiple‐bearing ewes (p < .05), moreover, its lowest value was measured at 1‐week prepartum in both groups. Throughout the study period, the serum concentrations of non‐esterified fatty acids (NEFA) were significantly increased in ewes with multiple lambs compared to ewes with single lambs (p < .05), and the highest value was found at 1‐week before parturition in both groups. In addition, the serum level of beta‐hydroxybutyric acid (BHBA) was higher at 3‐week postpartum, and it was significantly increased in multiple‐bearing ewes than that in single‐bearing ones (p < .05) at 3‐week pre‐lambing. In both groups, the lowest values of total proteins were determined 1‐week before lambing, and its concentrations, at 3‐ and 1‐week prepartum, were higher in ewes with single lambs than those with multiple lambs (p < .05). In contrast, the serum concentrations of albumin were significantly lowered 1‐week postpartum (p < .05), and without significant differences between both groups (p > .05). The serum activities of aspartate aminotransferase (AST) and gamma‐glutamyltransferase (GGT) were significantly increased at 1‐week after parturition in both groups (p < .05). Furthermore, the serum activities of AST were higher in multiple‐bearing ewes than those in single‐bearing ones at 3‐week pre‐lambing and 3‐week post‐lambing (p < .05). Variable positive and negative correlations were determined among the blood metabolites. In conclusion, physiological adaptations are associated with the fluctuation of the blood metabolites around lambing. The higher the number of foetuses the higher the metabolic variations in Ossimi ewes. Therefore, regular metabolic profiling for health monitoring may be necessary to avoid disease development during the transition period.

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“…This might relate to the differences between the breeds used and to the different metabolism of jennies during the transition period compared to non-pregnant jennies evaluated in the study by Quaresma and colleagues [ 11 ]. Pregnant jennies bred for milking production seem to be characterized by major physiological challenges related to energy balance and fat mobilization, as shown in cows [ 27 ].…”

Section: Discussionmentioning

confidence: 99%

“…No significant difference has been detected during the observation of different sites through time, except for S2 and S6a: S2 at T2 and S6a at T1 were significatively different to values obtained at T5. For cows a significant effect of the time on the mean values of backfat thickness during the peripartum period was detected [ 27 ]: the values decreased gradually from 30 days before until 60 days after calving, as the peak of lactation approaches [ 27 ]. In jennies, the lactation curve is variable from 8 to 12 weeks post-partum.…”

Section: Discussionmentioning

confidence: 99%

“…It usually presented 2 peaks, depending on the time of parturition: at 60 and 150 d in the summer group and a peak at 90 d in the spring group [ 28 ]. Approaching the peak of lactation might positively influence fat mobilization, since the first months of lactation led to difficulty in meeting the greater energy needs similarly to other dairy species [ 25 , 27 ]. In our study, differences were detected only in two sites probably because these are more susceptible to fat mobilization compared to others [ 12 , 13 ], which could be influenced since the earliest phase of lactation.…”

Section: Discussionmentioning

confidence: 99%

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Evaluation of Ultrasound Measurement of Subcutaneous Fat Thickness in Dairy Jennies during the Periparturient Period

Nocera

Bonelli

Turini

et al. 2022

Animals

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The body condition score (BCS) represents a practical but subjective method for assessing body fat reserves. Real time ultrasonography (RTU) has been proposed as an accurate method to objectively measure subcutaneous fat (SF) thickness and predict body fat reserves in cows, horses and donkeys. The aim of the present study was to describe RTU measures of SF thickness during periparturient period in jennies. The present prospective cohort study evaluated six dairy jennies. SF RTU were performed at 15 and 7 days before the presumptive delivery, and 2, 15 and 30 days after delivery. A portable ultrasound machine and multifrequency linear transducer (5–7.5 MHz) was used. RTU images were obtained in six sites (S1–S6). Results at each time point were reported as mean ± standard deviation and compared through time. A total of 180 images were evaluated. RTU technique was easy to perform and well tolerated. No statistically significant differences were found of each site during time, except for S2 and S6a: S2 at T2 and S6a at T1 were significatively different to values obtained at T5. The RTU mean values were above those reported by others, suggesting major physio-logical challenges related to energy balance and fat mobilization in pregnant jennies bred for milking production. BCS and sites through observational time have shown a good and reliable association. Our study could give preliminary indications on fat reserves in different body locations evaluated thanks to RTU and it show no significative variation of SF thickness, in pregnant and lactating jennies.

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The association between metabolic profile indices, clinical parameters, and ultrasound measurement of backfat thickness during the periparturient period of dairy cows

Cited by 5 publications

References 40 publications

24-h variations of blood serum metabolites in high yielding dairy cows and calves

24-h variations of blood serum metabolites in high yielding dairy cows and calves

Variations of blood metabolites in single‐ and multiple‐bearing Ossimi ewes during the transition period

Evaluation of Ultrasound Measurement of Subcutaneous Fat Thickness in Dairy Jennies during the Periparturient Period

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